Publikationen

Publikationen aus EVALUNA

Süß P, Regensburger M, Gassner H, Winkler J:(2026)Lifestyle medicine in Parkinson's disease.J Neural Transm. 2026;133(2): 279-295
Regensburger M, Csoti I, Jost WH, Kohl Z, Lorenzl S, Pedrosa DJ, Lingor P:(2026)Motor and non-motor fluctuations in Parkinson's disease: the knowns and unknowns of current therapeutic approaches.J Neural Transm. 2026;133(2): 309-324
Arnold P, Zunke F:(2026)Base and translation of β-glucocerebrosidase and its transporter LIMP-2 in neuropathies.Neural Regen Res. 2026;21(1): 314-315
Yarnall AJ, Alcock L, Schlenstedt C, Armengol C, Becker C, Brown P, Buekers J, Caulfield B, Cereatti A, Cordova-Rivera L, Del Din S, Delgado-Ortiz L, Forrest-Gordon M, Garcia-Aymeriche J, Goerrissen P, Hansen C, Hildesheim H, Hiden H, Hunter H, Jansen CP, Koch S, Kudelka J, Long M, Neatrour I, Sharrack B, Singleton D, Sutcliffe L, Troosters T, Winkler J, Ginis P, Gassner H, Nieuwboer A, Hausdorff JM, Mirelman A, Rochester L, Maetzler W:(2026)The future of clinical trials? Monitoring mobility as an outcome measure in Parkinson's disease: The mobilise-D study.J Parkinsons Dis. 2026;16(1): 110-124
Porsche S, Klietz M, Greten S, Piot IA, Jensen I, Wegner F, Ye L, Krey L, Höllerhage M, Pötter-Nerger M, Zeitzschel M, Hagena K, Kassubek J, Süß P, Winkler J, Berg D, Paschen S, Tönges L, Gruber D, Gandor F, Jost WH, Kühn AA, Claus I, Warnecke T, Pedrosa DJ, Eggers C, Trenkwalder C, Classen J, Schwarz J, Schnitzler A, Krause P, Schneider A, Brandt M, Falkenburger B, Zerr I, Bähr M, Weidinger E, Levin J, Katzdobler S, Düzel E, Glanz W, Teipel S, Kilimann I, Prudlo J, Gasser T, Brockmann K, Spottke A, Esser A, Petzold GC, Respondek G, Höglinger GU:(2025)A Short Cognitive and Neuropsychiatric Assessment Scale for Progressive Supranuclear Palsy.Mov Disord Clin Pract. 2025;12(6): 764-774
Ye L, Greten S, Wilkens I, Wegner F, Krey L, Höllerhage M, Pötter-Nerger M, Zeitzschel M, Hagena K, Kassubek J, Süß P, Winkler J, Berg D, Paschen S, Tönges L, Gruber D, Gandor F, Jost WH, Kühn AA, Claus I, Warnecke T, Pedrosa DJ, Eggers C, Trenkwalder C, Classen J, Schwarz J, Schnitzler A, Höglinger GU, Klietz M:(2025)Tackling gender in progressive supranuclear palsy: Male patients present more apathy.J Parkinsons Dis. 2025;15(5): 1024-1028
Arnold P, Boros FA, Mattner J, Seidel G, Liu C, Hensel IV, Van Deun J, Schwendner R, Müller-Deile J, Sopel N, Ramming A, Angeli MR, Rauber S, Vilhena C, Baur A, Wirtz S, Überla K, Reutter H, Mulzer LM, Hilger AC, Zunke F, Xiang W, Fuhrmann G, Günther C:(2025)Two Sides of the Same Coin-Mechanistic Insight, Diagnostic Application and Therapeutic Translation of Bacterial and Host-Derived Extracellular Vesicles.J Extracell Biol. 2025;4(11):
Balta D, Varghese A, Prieto Huarcaya S, Di Spiezio A, Marques ARA, Akdaş EY, Tabakacilar D, Drobny A, Werner C, Xiang W, Mächtel R, Dobert JP, Fejtova A, Richter F, Küspert M, Arnold P, Saftig P, Zunke F:(2025)Recombinant cathepsins B and L promote α-synuclein clearance and restore lysosomal function in human and murine models with α-synuclein pathology.Mol Neurodegener. 2025;20(1):
Hoffmann L, Eckl EM, Bérouti M, Pries M, Koller A, Guhl C, Hellmich UA, Hornung V, Xiang W, Jae LT, Kielkowski P:(2025)AMPylation Regulates 5'-3' Exonuclease PLD3 Processing.Mol Cell Proteomics. 2025;24(10):
Mulzer LM, Felger T, Muñoz LE, Engl G, Reutter H, Schiffer M, Jahromi LP, Boros FA, Zunke F, Arnold P, Hilger AC:(2025)Dynamic changes of extracellular vesicles during zebrafish organogenesis.Cell Commun Signal. 2025;23(1):
Weiss A, Meissner AF, Boros FA, Regensburger M, Taudte RV, Matamoros-Angles A, Arnold P, Zunke F:(2025)Transmission Electron Microscopy-based characterization of Extracellular Vesicles from plasma and serum from Parkinson´s Disease patients.Cell Commun Signal. 2025;23(1):
Schneider Y, Koller A, Schweigert A, Andert M, Hoffmann L, O'Brien S, Seebauer L, Plötz S, Kielkowski P, Winkler J, Schlachetzki JCM, Xiang W:(2025)Vimentin network dysregulation mediates neurite deficits in SNCA duplication Parkinson's patient-derived midbrain neurons.Sci Adv. 2025;11(23):
Lai TT, Xiang W, Stanojlovic M, Käufer C, Feja M, Lau K, Zunke F, Richter F:(2025)The basolateral amygdala and striatum propagate alpha-synuclein pathology causing increased fear response in a Parkinson's disease model.Brain Behav Immun. 2025;128(): 469-486
Dürholz K, Ehnes L, Linnerbauer M, Schmid E, Danzer H, Hinzpeter-Schmidt M, Lößlein L, Amend L, Frech M, Azizov V, Schälter F, Gessner A, Lucas S, Lesker TR, Taudte RV, Hofmann J, Beyer F, Bootz-Maoz H, Reich Y, Romano H, Mauro D, Beckervordersandforth R, Kragsnaes MS, Ellingsen T, Xiang W, Haghikia A, Akdis CA, Ciccia F, Bäuerle T, Sarter K, Strowig T, Yissachar N, Schett G, Rothhammer V, Zaiss MM:(2025)Gut-specific histamine 3 receptor signaling orchestrates microglia-dependent resolution of peripheral inflammation.J Clin Invest. 2025;135(18):
Masanetz RK, Mundlos H, Stolzer I, Winkler J, Günther C, Süß P:(2025)Absence of Microglial Activation and Maintained Hippocampal Neurogenesis in a Transgenic Mouse Model of Crohn's Disease.Cells. 2025;14(11):
Wihan J, Battis K, Hoffmann A, Windener F, Himmler M, Varghese A, Koller A, Karnatz I, Schubert DW, Zunke F, Xiang W, Kuhlmann T, Winkler J:(2025)Alpha synuclein-mediated cytoskeletal dysfunction impairs myelination in human oligodendrocytes.Acta Neuropathol (Berl). 2025;150(1):
Bluhm A, Xiang W, Wien F, Thureau A, Chevreuil M, Raynal B, Geissler S, Wermann M, Schilling S, Bénas P, Hartlage-Rübsamen M, Schulze A, Sauter C, Roßner S:(2025)Monomers, Dimers, and Oligomers of Pyroglutamate-Modified α-Synuclein Fragments Exhibit Distinct Biophysical Characteristics.ACS Chem Neurosci. 2025;16(10): 1919-1936
Pallett MA, Benesova I, Masanetz RK, van Gool MMJ, Diefenbach-Wilke ML, Hausmann A, Nabhan M:(2025)yEFIS with EFIS Lead the Way to ECR Engagement at ECI2024Eur J Immunol. 2025;55(4):
Kutscherauer RK, Meiser P, Wahida A, Afzali AM, Faust Akl CF, Esser-von Bieren J, Boztug K, Ullrich E:(2025)2025 German Society for Immunology PrizesEur J Immunol. 2025;55(9):
Mundlos H, Masanetz RK, Gauer C, Stolzer , Guenther C, Winkler J, Suess P:(2025)Maintained microglial homeostasis and adult neurogenesis despite chronic ileocolitisJ Crohns Colitis. 2025;19 Suppl _1(): i489-i489
Quattrone A, Franzmeier N, Levin J, Petzold GC, Spottke A, Brosseron F, Falkenburger B, Prudlo J, Gasser T, DESCRIBE‐PSP Group, The ProPSP Group , Höglinger GU, Petzold GC, Kimmich O, Falkenburger B, Dinter E, Höglinger GU, Palleis C, Bernhardt AM, Levin J, Katzdobler S, Jäck A, Prudlo J, Gasser T, Brockmann K, Spottke A, Gamez A, Brosseron F, Klietz M, Wegner F, Pötter-Nerger M, Pedrosa DJ, Eggers C, Mollenhauer B, Claus I, Regensburger M, Süß P, Warnecke T, Gandor F, Gruber D, Berg D, Paschen S, Claßen J, Kassubek J, Jost WH, Tönges L:(2025)Prospective Multicenter Evaluation of the MDS "Suggestive of PSP" Diagnostic Criteria.Mov Disord. 2025;40(3): 526-536
Lößlein L, Linnerbauer M, Zuber F, Tsaktanis T, Vandrey O, Peter A, Panier F, Zissler J, Riekher V, Bäuerle T, Hanspach J, Laun FB, Nagel L, Mészáros L, Zunke F, Winkler J, Naumann UJ, Schwingen N, Neumaier E, Liesz A, Quintana F, Rothhammer V:(2025)TGFα controls checkpoints in CNS resident and infiltrating immune cells to promote resolution of inflammation.Nat Commun. 2025;16(1):
Koch V, Ibrahim A, Winkler J, Eskofier B, Regensburger M, Gassner H:(2025)Outcome measures of instrumented gait analysis in hereditary spastic paraplegia: a systematic review.J Neuroeng Rehabil. 2025;22(1):
Bjelica B, Wohnrade C, Osmanovic A, Schreiber-Katz O, Koerner S, Kollewe K, Haeckl S, Freigang M, Cordts I, Becker B, Vogt C, Muhandes MT, Günther R, Deschauer M, Koch JC, Tuerk M, Regensburger M, Neuwirth C, Petri S:(2025)Compound Muscle Action Potential (CMAP) Amplitude Trajectories and Pattern in Adults with 5q-Spinal Muscular Atrophy Receiving Nusinersen Therapy: A Multicenter, Binational Observational Study.Eur J Neurol. 2025;32(11):
Boerstler T, Kachkin D, Gerasimova E, Zagha N, Furlanetto F, Nayebzade N, Zappia L, Boisvert M, Farrell M, Ploetz S, Prots I, Regensburger M, Günther C, Winkler J, Gupta P, Theis F, Karow M, Falk S, Winner B, Krach F:(2025)Deciphering brain organoid heterogeneity by identifying key quality determinants.Commun Biol. 2025;8(1):
Gerasimova E, Beenen AC, Kachkin D, Regensburger M, Zundler S, Blumenthal DB, Lutzny-Geier G, Winner B, Prots I:(2025)Novel co-culture model of T cells and midbrain organoids for investigating neurodegeneration in Parkinson's disease.NPJ Parkinsons Dis. 2025;11(1):
Alecu JE, Sigutova V, Brazdis RM, Lörentz S, Bogiongko ME, Nursaitova A, Regensburger M, Roybon L, Galler KM, Wrasidlo W, Winner B, Prots I:(2025)NPT100-18A rescues mitochondrial oxidative stress and neuronal degeneration in human iPSC-based Parkinson's model.BMC Neurosci. 2025;26(1):
Steffke C, Baskar K, Bachhuber F, Wiesenfarth M, Dorst J, Schuster J, Schöberl F, Reilich P, Regensburger M, German A, Günther R, Vidovic M, Petri S, Meyer T, Hagenacker T, Grosskreutz J, Weyen U, Weydt P, Haarmeier T, Lingor P, Wolf J, Hermann A, Prudlo J, Günther K, Knehr A, Elmas Z, Uzelac Z, Witzel S, Ruf WP, Freischmidt A, Ho R, Ludolph AC, Weishaupt JH, Tumani H, Oeckl P, Brenner D, Catanese A:(2025)Targeted Proteomics upon Treatment with Tofersen Identifies Novel Response Markers for Superoxide Dismutase 1-Linked Amyotrophic Lateral Sclerosis.Ann Neurol. 2025;98(6): 1318-1334
Mejia AC, Sapienza S, Paccoud I, Alcock L, Brown P, Gaßner H, Hunter H, Maetzler W, Mirelman A, Nieuwboer A, Regensburger M, Rochester L, Stallforth S, Vereijken B, Yarnall A, Klucken J:(2025)Consensus on the clinical utility of digital mobility outcomes for personalized clinical decision support in parkinson's disease.Neurol Res Pract. 2025;7(1):
Schwahn J, Hebestreit S, Kosche O, Steinacker P, Sandikci V, Winzer I, Hesebeck-Brinckmann J, Bachhuber F, Valkadinov I, Nittka S, Mesin L, Brauner M, von Arnim C, Santhanam N, Spreyer M, Sackmaier R, Knehr A, Barthel P, Bähr O, Gruber H, Stallforth S, Regensburger M, Winkler J, Yilmaz R, Neumaier M, Tumani H, Maros ME, Wenz H, Brenner D, Otto M, Ebert A, Conrad J, Weishaupt JH:(2025)Deep clinical, genetic, and serum biomarker profiling indicates glial and neuronal pathology in primary brain calcification.Brain Commun. 2025;7(6):
Dorschky E, Nitschke M, Mayer M, Weygers I, Gassner H, Seel T, Eskofier BM, Koelewijn AD:(2025)Comparing sparse inertial sensor setups for sagittal-plane walking and running reconstructions.Front Bioeng Biotechnol. 2025;13():
Kirk C, Packer E, Polhemus A, MacLean MK, Bailey H, Kluge F, Gaßner H, Rochester L, Del Din S, Yarnall AJ:(2025)A systematic review of real-world gait-related digital mobility outcomes in Parkinson's disease.NPJ Digit Med. 2025;8(1):
Lumsdon J, Wilson C, Alcock L, Becker C, Benvenuti F, Bonci T, van den Brande K, Brittain G, Brown P, Buckley E, Caruso M, Caulfield B, Cereatti A, Delgado-Ortiz L, Del Din S, Evers J, Garcia-Aymerich J, Gaßner H, Gur Arieh T, Hansen C, Hausdorff JM, Hiden H, Hume E, Kirk C, Maetzler W, Megaritis D, Rochester L, Scott K, Sharrack B, Sutton N, Vereijken B, Vogiatzis I, Yarnall A, Keogh A, Cantu A:(2025)Cocreating the Visualization of Digital Mobility Outcomes: Delphi-Type Process With Patients.JMIR Form Res. 2025;9():
Ghirotto B, Gonçalves LE, Ruder V, James C, Gerasimova E, Rizo T, Wend H, Farrell M, Gerez JA, Prymaczok NC, Kuijs M, Shulman M, Hartebrodt A, Prots I, Gessner A, Zunke F, Winkler J, Blumenthal DB, Theis FJ, Riek R, Günther C, Neurath M, Gupta P, Winner B:(2025)TNF-α disrupts the malate-aspartate shuttle, driving metabolic rewiring in iPSC-derived enteric neural lineages from Parkinson's Disease patients.bioRxiv. 2025;():
Krach F, Boerstler T, Neubert S, Krumm L, Regensburger M, Winkler J, Winner B:(2025)RNA splicing modulator for Huntington's disease treatment induces peripheral neuropathy.iScience. 2025;28(5):
Dobert JP, Schäfer JH, Dal Maso T, Ravindran P, Huard DJE, Socher E, Schildmeyer LA, Lieberman RL, Versées W, Moeller A, Zunke F, Arnold P:(2025)Cryo-TEM structure of β-glucocerebrosidase in complex with its transporter LIMP-2.Nat Commun. 2025;16(1):
Raschka T, To J, Hähnel T, Sapienza S, Ibrahim A, Glaab E, Gaßner H, Steidl R, Winkler J, Corvol JC, Klucken J, Fröhlich H:(2025)Objective monitoring of motor symptom severity and their progression in Parkinson's disease using a digital gait device.Sci Rep. 2025;15(1):
Furlanetto F, Flegel N, Kremp M, Spear C, Fröb F, Alfonsetti M, Bohl B, Krumbiegel M, Turan S, Reis A, Lie DC, Winkler J, Falk S, Wegner M, Karow M:(2025)A novel human organoid model system reveals requirement of TCF4 for oligodendroglial differentiation.Life Sci Alliance. 2025;8(6):
Zein L, Dietrich M, Balta D, Bader V, Scheuer C, Zellner S, Weinelt N, Vandrey J, Mari MC, Behrends C, Zunke F, Winklhofer KF, Van Wijk SJL:(2025)Linear ubiquitination at damaged lysosomes induces local NFKB activation and controls cell survival.Autophagy. 2025;21(5): 1075-1095
Krauss D, Richer R, Küderle A, Jukic J, German A, Leutheuser H, Regensburger M, Winkler J, Eskofier BM:(2025)Incorporating respiratory signals for machine learning-based multimodal sleep stage classification: a large-scale benchmark study with actigraphy and heart rate variability.Sleep. 2025;48(9):
German A, Tretter M:(2025)Brain Preservation and Cryonics Through the Lens of Moral PsychologyNEUROETHICS. 2025;18(1):
Greten S, Wegner F, Jensen I, Krey L, Rogozinski S, Fehring M, Heine J, Doll-Lee J, Pötter-Nerger M, Zeitzschel M, Hagena K, Pedrosa DJ, Eggers C, Bürk K, Trenkwalder C, Claus I, Warnecke T, Süß P, Winkler J, Gruber D, Gandor F, Berg D, Paschen S, Classen J, Pinkhardt EH, Kassubek J, Jost WH, Tönges L, Kühn AA, Schwarz J, Peters O, Dashti E, Priller J, Spruth EJ, Krause P, Spottke A, Schneider A, Beyle A, Kimmich O, Donix M, Haussmann R, Brandt M, Dinter E, Wiltfang J, Schott BH, Zerr I, Bähr M, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Weidinger E, Levin J, Katzdobler S, Düzel E, Glanz W, Teipel S, Kilimann I, Prudlo J, Gasser T, Brockmann K, Hoffmann DC, Klockgether T, Krause O, Heck J, Höglinger GU, Klietz M:(2024)The comorbidity and co-medication profile of patients with progressive supranuclear palsy.J Neurol. 2024;271(2): 782-793
Sankowski R, Süß P, Benkendorff A, Böttcher C, Fernandez-Zapata C, Chhatbar C, Cahueau J, Monaco G, Gasull AD, Khavaran A, Grauvogel J, Scheiwe C, Shah MJ, Heiland DH, Schnell O, Markfeld-Erol F, Kunze M, Zeiser R, Priller J, Prinz M:(2024)Multiomic spatial landscape of innate immune cells at human central nervous system borders.Nat Med. 2024;30(1): 186-198
Mészáros L, Himmler M, Schneider Y, Arnold P, Dörje F, Schubert DW, Winkler J:(2024)Sobetirome rescues α-synuclein-mediated demyelination in an in vitro model of multiple system atrophy.Eur J Neurosci. 2024;59(2): 308-315
Schneider Y, Gauer C, Andert M, Hoffmann A, Riemenschneider MJ, Krebs W, Chalmers N, Lötzsch C, Naumann UJ, Xiang W, Rothhammer V, Beckervordersandforth R, Schlachetzki JCM, Winkler J:(2024)Distinct forebrain regions define a dichotomous astrocytic profile in multiple system atrophy.Acta Neuropathol Commun. 2024;12(1):
Moceri S, Bäuerle N, Habermeyer J, Ratz-Wirsching V, Harrer J, Distler J, Schulze-Krebs A, Timotius IK, Bluhm A, Hartlage-Rübsamen M, Roßner S, Winkler J, Xiang W, Hörsten SV:(2024)Young human alpha synuclein transgenic (BAC-SNCA) mice display sex- and gene-dose-dependent phenotypic disturbances.Behav Brain Res. 2024;460():
Xiang W, Vicente Miranda H:(2024)Unraveling the complexity of alpha-synucleinopathies: Insights from the special issue "alpha synuclein and synucleinopathies".Behav Brain Res. 2024;460():
Kirk C, Küderle A, Micó-Amigo ME, Bonci T, Paraschiv-Ionescu A, Ullrich M, Soltani A, Gazit E, Salis F, Alcock L, Aminian K, Becker C, Bertuletti S, Brown P, Buckley E, Cantu A, Carsin AE, Caruso M, Caulfield B, Cereatti A, Chiari L, D'Ascanio I, Garcia-Aymerich J, Hansen C, Hausdorff JM, Hiden H, Hume E, Keogh A, Kluge F, Koch S, Maetzler W, Megaritis D, Mueller A, Niessen M, Palmerini L, Schwickert L, Scott K, Sharrack B, Sillén H, Singleton D, Vereijken B, Vogiatzis I, Yarnall AJ, Rochester L, Mazzà C, Eskofier BM, Del Din S, Mobilise-D consortium , Bottin F, Chiari L, Curreli C, D'Ascanio I, Davico G, De Michele R, Galimberti G, Palmerini L, Ranciati S, Reggi L, Viceconti M, D'Apote L, Desmond J, Doyle M, Elliot-Davey M, Gnacadja G, Kassner A, Knusel B, Pocrzepa M, Pourbaix N, Radcliffe HS, Shen L, Simon J, Havsol J, Jarretta D, Jornten-Karlsson M, Mugnier P, Rohou SC, Saraiva G, Sillén H, Boettger M, Knezevic I, Kramer F, Piraino P, Trübel H, Ahachad H, Blain H, Broussous S, Canovas F, Cerret F, Dagneaux L, Driss V, Galtier F, Kaan C, Miot S, Murauer E, Vérissimo AS, Berg D, Emmert K, Hansen C, Hildesheim H, Kudelka J, Maetzler W, Maetzler C, Schlenstedt C, Arnera V, Beckstrom K, Folaron P, Gizdic A, Horak F, Imeri S, Krieger S, Nica N, Pletneva N, Raymond S, Reed D, Sekaram A, Sowalsky K, Aminian K, Ionescu A, Soltani A, Eskofier B, Kluge F, Küderle A, Ullrich M, Serrano VA, de Basea MB, Buekers J, Cardenas G, Carsin AE, Cobo I, Llobet AD, Ortiz LD, Garcia MF, Aymerich JG, Gimeno-Santos E, Jose A, Koch S, Ahmad A, Froehlich M, Borlikova G, Edieux MS, Fox R, Holt B, Howard K, Kelly S, Kelly S, Lalor R, Malouvier A, Ramanna KM, Mc Carthy M, Quinn G, Chavez IR, Schueler P, Skackov M, Skerrit B, Buttery S, Hopkinson N, Perkins A, Philip K, Polkey M, Williams P, Jackson M, Wenn D, Breuls S, Demeyer H, Ghosh N, Ginis P, Glorie L, Haerens V, Hulst L, Hulzinga F, Janssenns W, Nieuwboer A, Troosters T, Vanhoutte T, Witvrouw M, Wuyts M, Cornelisse L, Evers J, Frouws S, Mouthaan N, Niessen M, Siepman L, Aydemir A, Hyvert Y, Berge MA, Diaconu M, Engdal M, Grønvik KB, Helbostad J, Johnsen LG, Marcuzzi A, Midtsand I, Odden M, Saltvedt I, Skaslien E, Taraldsen K, Vereijken B, Bunte O, Dartee W, Erdemli G, Grenet O, Hache T, Hariry S, Penna SH, Kluge F, Lukawy J, Maahs S, Miller R, Mueller A, Praestgaard J, Roubenoff R, Schluechter S, van Steenbergen L, Cai X, Demanuele C, Demanuele C, Gameiro M, Junrui D, Karahanoglu I, Mather J, Psaltos D, Stokes E, Tarachandani A, Zhang H, Kirsten AM, Paash K, Russ M, Watz H, Zimmermann I, Becker C, Brenner N, Endress C, Gierka M, Huber C, Jaeger S, Jansen CP, Kinner B, Klenk J, Litz E, Litz E, Mikolaizak S, Rapp K, Schwab M, Schwickert L, Uysal E, Wohlrab M, Zoller V, Ammour N, Bascle S, Bonche F, Cariou M, Jouannin M, Chambers M, Ciucchiuini A, Dowling A, Merlo-Pich E, Tolkoff M, Fry L, Gordon M, Loupe P, Melamed M, Reich M, Shnider S, Brozgol M, Buzaglo D, Thumm PC, Gazit E, Giladi N, Hausdorff J, Herman T, Hillel I, Mirelman A, Saban A, Yehezkyahu S, Chynkiamis N, Bertuletti S, Caruso M, AndreaCereatti , Manca A, Salis F, Bonanno V, Brichetto G, Costa GD, Giancarlo C, Leocani L, Mahajneh A, Martinis M, Rodegher M, Tacchino A, Zaffaroni M, Zaffaroni M, Buesching G, Frei A, Hackl K, Keller M, Maggi-Beba M, Polhemus A, Puhan M, Riegler T, Sigrist T, Spielmanns S, Spielmanns M, Zumbrunnen V, Dettmer S, Gassner H, Greinwalder T, Huhn K, Jukic J, Klucken J, Marxreiter F, Nickel F, Regensburger M, Rothhammer V, Seifferth S, Stallforth S, Stirnweiß T, Weitzenfelder A, Winkler J, Bevilaqua A, Caulfield B, Goulding C, Ifrim G, Kechadi T, Keogh A, Mac Namee B, Philip M, Singleton D, Alcock L, Armitage G, Bacardit J, Bailey H, Brown P, Cantu A, Cordova-Rivera L, Del Din S, Galna B, Gibson A, Hart A, Hiden H, Hinchliffe C, Fernstad SJ, Kirk C, Lirani-Silva E, Amigo EM, Neatrour I, Packer E, Pantall A, Shi JQ, Rochester L, Hume E, Megaritis D, Vogiatzis I, Birchall S, Bonci T, Brittain G, Buckley E, Ciravegna F, Han S, Haslam L, Ireson N, Ishmail A, Islam M, Lanfranchi V, Long M, Mazzà C, McNeil J, Misraq S, Moll S, Mubarak-Mohamed A, Nair S, Paling D, Patel S, Pattanaik D, Priest D, Radford A, Scott K, Sharrack B, Vaci L, Van Gelder L:(2024)Mobilise-D insights to estimate real-world walking speed in multiple conditions with a wearable device.Sci Rep. 2024;14(1):
Linnerbauer M, Lößlein L, Vandrey O, Peter A, Han Y, Tsaktanis T, Wogram E, Needhamsen M, Kular L, Nagel L, Zissler J, Andert M, Meszaros L, Hanspach J, Zuber F, Naumann UJ, Diebold M, Wheeler MA, Beyer T, Nirschl L, Cirac A, Laun FB, Günther C, Winkler J, Bäuerle T, Jagodic M, Hemmer B, Prinz M, Quintana FJ, Rothhammer V:(2024)The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology.Nat Immunol. 2024;25(3): 432-447
Ibrahim AA, Ollenschläger M, Klebe S, Schüle R, Jeschonneck N, Kellner M, Loris E, Greinwalder T, Eskofier BM, Winkler J, Gaßner H, Regensburger M:(2024)Mobile digital gait analysis captures effects of botulinum toxin in hereditary spastic paraplegia.Eur J Neurol. 2024;31(8):
Raschka T, Li Z, Gaßner H, Kohl Z, Jukic J, Marxreiter F, Fröhlich H:(2024)Unraveling progression subtypes in people with Huntington's disease.EPMA J. 2024;15(2): 275-287
Raccagni C, Sidoroff V, Paraschiv-Ionescu A, Roth N, Schönherr G, Eskofier B, Gassner H, Kluge F, Teatini F, Seppi K, Goebel G, Benninger DH, Aminian K, Klucken J, Wenning G:(2024)Effects of physiotherapy and home-based training in parkinsonian syndromes: protocol for a randomised controlled trial (MobilityAPP).BMJ Open. 2024;14(5):
Shanbhag J, Fleischmann S, Wechsler I, Gassner H, Winkler J, Eskofier BM, Koelewijn AD, Wartzack S, Miehling J:(2024)A sensorimotor enhanced neuromusculoskeletal model for simulating postural control of upright standing.Front Neurosci. 2024;18():
Rosh I, Tripathi U, Hussein Y, Rike WA, Djamus J, Shklyar B, Manole A, Houlden H, Winkler J, Gage FH, Stern S:(2024)Synaptic dysfunction and extracellular matrix dysregulation in dopaminergic neurons from sporadic and E326K-GBA1 Parkinson's disease patients.NPJ Parkinsons Dis. 2024;10(1):
Krumm L, Pozner T, Zagha N, Coras R, Arnold P, Tsaktanis T, Scherpelz K, Davis MY, Kaindl J, Stolzer I, Süß P, Khundadze M, Hübner CA, Riemenschneider MJ, Baets J, Günther C, Jayadev S, Rothhammer V, Krach F, Winkler J, Winner B, Regensburger M:(2024)Neuroinflammatory disease signatures in SPG11-related hereditary spastic paraplegia patients.Acta Neuropathol (Berl). 2024;147(1):
Krumm L, Winkler J, Winner B, Regensburger M:(2024)Plasma Neurofilaments: Potential Biomarkers of SPG11-Related Hereditary Spastic Paraplegia.Mov Disord. 2024;39(4): 755-757
Wiesenfarth M, Forouhideh-Wiesenfarth Y, Elmas Z, Parlak Ö, Weiland U, Herrmann C, Schuster J, Freischmidt A, Müller K, Siebert R, Günther K, Fröhlich E, Knehr A, Simak T, Bachhuber F, Regensburger M, Petri S, Klopstock T, Reilich P, Schöberl F, Schumann P, Körtvélyessy P, Meyer T, Ruf WP, Witzel S, Tumani H, Brenner D, Dorst J, Ludolph AC:(2024)Clinical characterization of common pathogenic variants of SOD1-ALS in Germany.J Neurol. 2024;271(10): 6667-6679
Weishaupt JH, Körtvélyessy P, Schumann P, Valkadinov I, Weyen U, Hesebeck-Brinckmann J, Weishaupt K, Endres M, Andersen PM, Regensburger M, Dreger M, Koch JC, Conrad J, Meyer T:(2024)Tofersen decreases neurofilament levels supporting the pathogenesis of the SOD1 p.D91A variant in amyotrophic lateral sclerosis patients.Commun Med (Lond). 2024;4(1):
Meyer T, Schumann P, Weydt P, Petri S, Weishaupt JH, Weyen U, Koch JC, Günther R, Regensburger M, Boentert M, Wiesenfarth M, Koc Y, Kolzarek F, Kettemann D, Norden J, Bernsen S, Elmas Z, Conrad J, Valkadinov I, Vidovic M, Dorst J, Ludolph AC, Hesebeck-Brinckmann J, Spittel S, Münch C, Maier A, Körtvélyessy P:(2024)Clinical and patient-reported outcomes and neurofilament response during tofersen treatment in SOD1-related ALS-A multicenter observational study over 18 months.Muscle Nerve. 2024;70(3): 333-345
Sigutova V, Xiang W, Regensburger M, Winner B, Prots I:(2024)Alpha-synuclein fine-tunes neuronal response to pro-inflammatory cytokines.Brain Behav Immun. 2024;122(): 216-230
Mächtel R, Dobert JP, Hehr U, Weiss A, Kettwig M, Laugwitz L, Groeschel S, Schmidt M, Arnold P, Regensburger M, Zunke F:(2024)Late-onset Krabbe disease presenting as spastic paraplegia - implications of GCase and CTSB/D.Ann Clin Transl Neurol. 2024;11(7): 1715-1731
Linse K, Weber C, Reilich P, Schöberl F, Boentert M, Petri S, Rödiger A, Posa A, Otto M, Wolf J, Zeller D, Brunkhorst R, Koch J, Hermann A, Großkreutz J, Schröter C, Groß M, Lingor P, Machetanz G, Semmler L, Dorst J, Lulé D, Ludolph A, Meyer T, Maier A, Metelmann M, Regensburger M, Winkler J, Schrank B, Kohl Z, Hagenacker T, Brakemeier S, Weyen U, Weiler M, Lorenzl S, Bublitz S, Weydt P, Grehl T, Kotterba S, Lapp HS, Freigang M, Vidovic M, Aust E, Günther R:(2024)Patients' and caregivers' perception of multidimensional and palliative care in amyotrophic lateral sclerosis - protocol of a German multicentre study.Neurol Res Pract. 2024;6(1):
Wiesenfarth M, Dorst J, Brenner D, Elmas Z, Parlak Ö, Uzelac Z, Kandler K, Mayer K, Weiland U, Herrmann C, Schuster J, Freischmidt A, Müller K, Siebert R, Bachhuber F, Simak T, Günther K, Fröhlich E, Knehr A, Regensburger M, German A, Petri S, Grosskreutz J, Klopstock T, Reilich P, Schöberl F, Hagenacker T, Weyen U, Günther R, Vidovic M, Jentsch M, Haarmeier T, Weydt P, Valkadinov I, Hesebeck-Brinckmann J, Conrad J, Weishaupt JH, Schumann P, Körtvélyessy P, Meyer T, Ruf WP, Witzel S, Senel M, Tumani H, Ludolph AC:(2024)Effects of tofersen treatment in patients with SOD1-ALS in a "real-world" setting - a 12-month multicenter cohort study from the German early access program.EClinicalMedicine. 2024;69():
Dobert JP, Bub S, Mächtel R, Januliene D, Steger L, Regensburger M, Wilfling S, Chen JX, Dejung M, Plötz S, Hehr U, Moeller A, Arnold P, Zunke F:(2024)Activation and Purification of ß-Glucocerebrosidase by Exploiting its Transporter LIMP-2 - Implications for Novel Treatment Strategies in Gaucher's and Parkinson's Disease.Adv Sci (Weinh). 2024;11(25):
Riera C, de Oliveira DS, Borutta M, Regensburger M, Zhao Y, Brenner S, Del Vecchio A, Kinfe TM:(2024)Unaltered Responses of Distal Motor Neurons to Non-Targeted Thoracic Spinal Cord Stimulation in Chronic Pain Patients.Pain Ther. 2024;13(6): 1645-1658
Seufert CG, Borutta MC, Regensburger M, Zhao Y, Kinfe T:(2024)New Perspectives for Spinal Cord Stimulation in Parkinson's Disease-Associated Gait Impairment: A Systematic Review.Biomedicines. 2024;12(8):
Kluge A, Schaeffer E, Bunk J, Sommerauer M, Röttgen S, Schulte C, Roeben B, von Thaler AK, Welzel J, Lucius R, Heinzel S, Xiang W, Eschweiler GW, Maetzler W, Suenkel U, Berg D:(2024)Detecting Misfolded α-Synuclein in Blood Years before the Diagnosis of Parkinson's Disease.Mov Disord. 2024;39(8): 1289-1299
Gauer C, Battis K, Schneider Y, Florio JB, Mante M, Kim HY, Rissman RA, Hoffmann A, Winkler J:(2024)CSF1R-mediated myeloid cell depletion shifts the ratio of motor cortical excitatory to inhibitory neurons in a multiple system atrophy model.Exp Neurol. 2024;374():
Bernhardt AM, Nemati M, Boros FA, Hopfner F, Levin J, Mollenhauer B, Winkler J, Zerr I, Zunke F, Höglinger G:(2024)α-Synuclein Seed Amplification Assays from Blood-Based Extracellular Vesicles in Parkinson's Disease: An Evaluation of the Evidence.Mov Disord. 2024;39(8): 1269-1271
Wani WY, Zunke F, Belur NR, Mazzulli JR:(2024)The hexosamine biosynthetic pathway rescues lysosomal dysfunction in Parkinson's disease patient iPSC derived midbrain neurons.Nat Commun. 2024;15(1):
Bolsinger MM, Drobny A, Wilfling S, Reischl S, Krach F, Moritz R, Balta D, Hehr U, Sock E, Bleibaum F, Hanses F, Winner B, Huarcaya SP, Arnold P, Zunke F:(2024)SARS-CoV-2 Spike Protein Induces Time-Dependent CTSL Upregulation in HeLa Cells and Alveolarspheres.J Cell Biochem. 2024;125(9):
Kuderle A, Ullrich M, Roth N, Ollenschlager M, Ibrahim AA, Moradi H, Richer R, Seifer AK, Zurl M, Simpetru RC, Herzer L, Prossel D, Kluge F, Eskofier BM:(2024)Gaitmap-An Open Ecosystem for IMU-Based Human Gait Analysis and Algorithm Benchmarking.IEEE Open J Eng Med Biol. 2024;5(): 163-172
Jensen I, Stiel S, Bebermeier S, Schrag A, Greten S, Doll-Lee J, Wegner F, Ye L, Heine J, Krey L, Höllerhage M, Süß P, Winkler J, Berg D, Paschen S, Tönges L, Gruber D, Gandor F, Jost WH, Kühn AA, Claus I, Warnecke T, Pedrosa DJ, Eggers C, Trenkwalder C, Classen J, Schwarz J, Pötter-Nerger M, Kassubek J, Schnitzler A, Höglinger GU, Klietz M:(2024)A Short Progressive Supranuclear Palsy Quality of Life Scale.Mov Disord. 2024;39(9): 1602-1609
Paccoud I, Valero MM, Marín LC, Bontridder N, Ibrahim A, Winkler J, Fomo M, Sapienza S, Khoury F, Corvol JC, Fröhlich H, Klucken J:(2024)Patient perspectives on the use of digital medical devices and health data for AI-driven personalised medicine in Parkinson's Disease.Front Neurol. 2024;15():
Kremp M, Aberle T, Sock E, Bohl B, Hillgärtner S, Winkler J, Wegner M:(2024)Transcription factor Olig2 is a major downstream effector of histone demethylase Phf8 during oligodendroglial development.Glia. 2024;72(8): 1435-1450
Kalinichenko LS, Kohl Z, Mühle C, Hassan Z, Hahn A, Schmitt EM, Macht K, Stoyanov L, Moghaddami S, Bilbao R, Eulenburg V, Winkler J, Kornhuber J, Müller CP:(2024)Sex-specific pleiotropic changes in emotional behavior and alcohol consumption in human α-synuclein A53T transgenic mice during early adulthood.J Neurochem. 2024;168(3): 269-287
Gerschel T, Prokop S, Schulze L, Feige T, Zschieschang A, Barbe MT, Bitterlich R, Caffier J, Csoti I, Eggers C, Gaßner H, Gülke E, Hähnel T, Herbst H, Jochim A, Kiparski A, Klietz M, von Liel A, Lingor P, Loewenbrück K, Maetzler W, Pürner D, van Riesen C, Schmitz-Pfeiffer H, Süß T, Tönges L, Weiß D, Wolz M, Falkenburger B:(2024)[How the implementation of a school for people with Parkinson's disease can succeed-Results of a consensus study and a formative evaluation].Nervenarzt. 2024;95(6): 539-543
Saarela D, Lis P, Gomes S, Nirujogi RS, Dong W, Rawat E, Glendinning S, Zeneviciute K, Bagnoli E, Fasimoye R, Lin C, Nyame K, Boros FA, Zunke F, Lamoliatte F, Elshani S, Jaconelli M, Jans JJ, Huisman MA, Posern C, Westermann LM, Schulz A, van Hasselt PM, Alessi DR, Abu-Remaileh M, Sammler EM:(2024)Tagless LysoIP for immunoaffinity enrichment of native lysosomes from clinical samples.J Clin Invest. 2024;135(4):
Kluge A, Bunk J, Schaeffer E, Drobny A, Xiang W, Knacke H, Bub S, Lueckstaedt W, Arnold P, Lucius R, Berg D, Zunke F:(2023)Detection of neuron-derived pathological alpha-synuclein in blood (vol 145, pg 3058, 2022)Brain. 2023;146(1): E6-E6
Regensburger M, Rasul Chaudhry S, Yasin H, Zhao Y, Stadlbauer A, Buchfelder M, Kinfe T:(2023)Emerging roles of leptin in Parkinson's disease: Chronic inflammation, neuroprotection and more?Brain Behav Immun. 2023;107(): 53-61
Mennecke A, Khakzar KM, German A, Herz K, Fabian MS, Liebert A, Blümcke I, Kasper BS, Nagel AM, Laun FB, Schmidt M, Winkler J, Dörfler A, Zaiss M:(2023)7 tricks for 7 T CEST: Improving the reproducibility of multipool evaluation provides insights into the effects of age and the early stages of Parkinson's disease.NMR Biomed. 2023;36(6):
Ullrich M, Roth N, Kuderle A, Richer R, Gladow T, Gasner H, Marxreiter F, Klucken J, Eskofier BM, Kluge F:(2023)Fall Risk Prediction in Parkinson's Disease Using Real-World Inertial Sensor Gait Data.IEEE J Biomed Health Inform. 2023;27(1): 319-328
Tavares JED, Ullrich M, Roth N, Kluge F, Eskofier BM, Gassner H, Klucken J, Gladow T, Marxreiter F, da Costa CA, Righi RD, Barbosa JLV:(2023)uTUG: An unsupervised Timed Up and Go test for Parkinson's diseaseBiomed. Signal Process. Control. 2023;81():
Mächtel R, Annamaria Boros F, Philipp Dobert J, Arnold P, Zunke F:(2023)From Lysosomal Storage Disorders to Parkinson's Disease - Challenges and Opportunities.J Mol Biol. 2023;435(12):
Drobny A, Boros FA, Balta D, Prieto Huarcaya S, Caylioglu D, Qazi N, Vandrey J, Schneider Y, Dobert JP, Pitcairn C, Mazzulli JR, Zunke F:(2023)Reciprocal effects of alpha-synuclein aggregation and lysosomal homeostasis in synucleinopathy models.Transl Neurodegener. 2023;12(1):
Wöhner B, Li W, Hey S, Drobny A, Werny L, Becker-Pauly C, Lucius R, Zunke F, Linder S, Arnold P:(2023)Proteolysis of CD44 at the cell surface controls a downstream protease network.Front Mol Biosci. 2023;10():
Prieto Huarcaya S, Zunke F:(2023)Therapeutic potential of lysosomal cathepsins for neurodegenerative diseases.Neural Regen Res. 2023;18(8): 1713-1714
Schmitt V, Masanetz RK, Weidenfeller M, Ebbinghaus LS, Süß P, Rosshart SP, von Hörsten S, Zunke F, Winkler J, Xiang W:(2023)Gut-to-brain spreading of pathology in synucleinopathies: A focus on molecular signalling mediators.Behav Brain Res. 2023;452():
Heinrich F, Cordts I, Günther R, Stolte B, Zeller D, Schröter C, Weyen U, Regensburger M, Wolf J, Schneider I, Hermann A, Metelmann M, Kohl Z, Linker RA, Koch JC, Radelfahr F, Schönfelder E, Gardt P, Mohajer-Peseschkian T, Osmanovic A, Klopstock T, Dorst J, Ludolph AC, Schöffski O, Boentert M, Hagenacker T, Deschauer M, Lingor P, Petri S, Schreiber-Katz O:(2023)Economic evaluation of Motor Neuron Diseases: a nationwide cross-sectional analysis in Germany.J Neurol. 2023;270(10): 4922-4938
Ollenschläger M, Höfner P, Ullrich M, Kluge F, Greinwalder T, Loris E, Regensburger M, Eskofier BM, Winkler J, Gaßner H:(2023)Automated assessment of foot elevation in adults with hereditary spastic paraplegia using inertial measurements and machine learning.Orphanet J Rare Dis. 2023;18(1):
Loris E, Ollenschläger M, Greinwalder T, Eskofier B, Winkler J, Gaßner H, Regensburger M:(2023)Mobile digital gait analysis objectively measures progression in hereditary spastic paraplegia.Ann Clin Transl Neurol. 2023;10(3): 447-452
Marxreiter F, Lambrecht V, Mennecke A, Hanspach J, Jukic J, Regensburger M, Herrler J, German A, Kassubek J, Grön G, Müller HP, Laun FB, Dörfler A, Winkler J, Schmidt MA:(2023)Parkinson's disease or multiple system atrophy: potential separation by quantitative susceptibility mapping.Therap Adv Neurol Dis. 2023;16():
Koch V, Jakob V, Kuderle A, Ollenschlaeger M, Kathrin K, Ibrahim A, Winkler J, Eskofier BM, Regensburger M, Gasner H:(2023)Inertial sensor acquired foot elevation parameters validated by Motion capture in a cohort of patients with Hereditary Spastic ParaplegiasGait Posture. 2023;100 Suppl 1(): 79-80
Masanetz RK, Baum W, Schett G, Winkler J, Süß P:(2023)Cellular plasticity and myeloid inflammation in the adult brain are independent of the transcriptional modulator DREAM.Neurosci Lett. 2023;796():
Wiesenfarth M, Günther K, Müller K, Witzel S, Weiland U, Mayer K, Herrmann C, Brenner D, Schuster J, Freischmidt A, Lulé D, Meyer T, Regensburger M, Grehl T, Emmer A, Petri S, Großkreutz J, Rödiger A, Steinbach R, Klopstock T, Reilich P, Schöberl F, Wolf J, Hagenacker T, Weyen U, Zeller D, Ludolph AC, Dorst J:(2023)Clinical and genetic features of amyotrophic lateral sclerosis patients with C9orf72 mutations.Brain Commun. 2023;5(2):
Beerweiler CC, Masanetz RK, Schaub B:(2023)Asthma and allergic diseases: Cross talk of immune system and environmental factors.Eur J Immunol. 2023;53(6):
Regensburger M, Ip CW, Kohl Z, Schrader C, Urban PP, Kassubek J, Jost WH:(2023)Clinical benefit of MAO-B and COMT inhibition in Parkinson's disease: practical considerations.J Neural Transm. 2023;130(6): 847-861
Ibrahim AA, Adler W, Gaßner H, Rothhammer V, Kluge F, Eskofier BM:(2023)Association between cognition and gait in multiple sclerosis: A smartphone-based longitudinal analysis.Int J Med Inform. 2023;177():
Zahn A, Koch V, Schreff L, Oschmann P, Winkler J, Gaßner H, Müller R:(2023)Validity of an inertial sensor-based system for the assessment of spatio-temporal parameters in people with multiple sclerosis.Front Neurol. 2023;14():
Battis K, Xiang W, Winkler J:(2023)The Bidirectional Interplay of α-Synuclein with Lipids in the Central Nervous System and Its Implications for the Pathogenesis of Parkinson's Disease.Int J Mol Sci. 2023;24(17):
Shanbhag J, Wolf A, Wechsler I, Fleischmann S, Winkler J, Leyendecker S, Eskofier BM, Koelewijn AD, Wartzack S, Miehling J:(2023)Methods for integrating postural control into biomechanical human simulations: a systematic review.J Neuroeng Rehabil. 2023;20(1):
Ruf WP, Boros M, Freischmidt A, Brenner D, Grozdanov V, de Meirelles J, Meyer T, Grehl T, Petri S, Grosskreutz J, Weyen U, Guenther R, Regensburger M, Hagenacker T, Koch JC, Emmer A, Roediger A, Steinbach R, Wolf J, Weishaupt JH, Lingor P, Deschauer M, Cordts I, Klopstock T, Reilich P, Schoeberl F, Schrank B, Zeller D, Hermann A, Knehr A, Günther K, Dorst J, Schuster J, Siebert R, Ludolph AC, Müller K:(2023)Spectrum and frequency of genetic variants in sporadic amyotrophic lateral sclerosis.Brain Commun. 2023;5(3):
Qassim H, Zhao Y, Ströbel A, Regensburger M, Buchfelder M, de Oliveira DS, Del Vecchio A, Kinfe T:(2023)Deep Brain Stimulation for Chronic Facial Pain: An Individual Participant Data (IPD) Meta-Analysis.Brain Sci. 2023;13(3):
Lützow L, Teckenburg I, Koch V, Marxreiter F, Jukic J, Stallforth S, Regensburger M, Winkler J, Klucken J, Gaßner H:(2023)The effects of an individualized smartphone-based exercise program on self-defined motor tasks in Parkinson's disease: a long-term feasibility study.J Patient Rep Outcomes. 2023;7(1):
Brittain G, Buckley E, Chakraborty S, Comi G, Costa GD, Gassner H, Leocani L, Martinis M, Rothhammer V, Stuerner K, Becker C, Rochester L, Sharrack B, Study Grp Mobilise-D:(2023)Quality of real world walking is reflective of disease severity - results from MOBILISE-D; the largest trial of Digital Mobility Outcome measures in Multiple SclerosisMult Scler. 2023;29 Suppl 3(): 316-317
German A, Jukic J, Laner A, Arnold P, Socher E, Mennecke A, Schmidt MA, Winkler J, Abicht A, Regensburger M:(2023)Novel Homozygous FA2H Variant Causing the Full Spectrum of Fatty Acid Hydroxylase-Associated Neurodegeneration (SPG35).Genes (Basel). 2023;15(1):
Schmidt S, Stautner C, Vu DT, Heinz A, Regensburger M, Karayel O, Trümbach D, Artati A, Kaltenhäuser S, Nassef MZ, Hembach S, Steinert L, Winner B, Jürgen W, Jastroch M, Luecken MD, Theis FJ, Westmeyer GG, Adamski J, Mann M, Hiller K, Giesert F, Vogt Weisenhorn DM, Wurst W:(2023)A reversible state of hypometabolism in a human cellular model of sporadic Parkinson's disease.Nat Commun. 2023;14(1):
Menon R, Petrucci L, Lohrer B, Zhang J, Schulze M, Schichor C, Winner B, Winkler J, Riemenschneider MJ, Kühn R, Falk S, Karow M:(2023)Human Induced Pluripotent Stem Cell-Derived Pericytes as Scalable and Editable Source to Study Direct Lineage Reprogramming Into Induced Neurons.Cell Reprogram. 2023;25(5): 212-223
Stolzer I, Scherer E, Süß P, Rothhammer V, Winner B, Neurath MF, Günther C:(2023)Impact of Microbiome-Brain Communication on Neuroinflammation and Neurodegeneration.Int J Mol Sci. 2023;24(19):
Regensburger M, Kinfe TM:(2023)Role of the adipocyte immune brain axis in Parkinson's disease: friend or foe?Neural Regen Res. 2023;18(11): 2399-2400
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Keogh A, Mc Ardle R, Diaconu MG, Ammour N, Arnera V, Balzani F, Brittain G, Buckley E, Buttery S, Cantu A, Corriol-Rohou S, Delgado-Ortiz L, Duysens J, Forman-Hardy T, Gur-Arieh T, Hamerlijnck D, Linnell J, Leocani L, McQuillan T, Neatrour I, Polhemus A, Remmele W, Saraiva I, Scott K, Sutton N, van den Brande K, Vereijken B, Wohlrab M, Rochester L, Mobilise-D consortium:(2023)Mobilizing Patient and Public Involvement in the Development of Real-World Digital Technology Solutions: Tutorial.J Med Internet Res. 2023;25():
Micó-Amigo ME, Bonci T, Paraschiv-Ionescu A, Ullrich M, Kirk C, Soltani A, Küderle A, Gazit E, Salis F, Alcock L, Aminian K, Becker C, Bertuletti S, Brown P, Buckley E, Cantu A, Carsin AE, Caruso M, Caulfield B, Cereatti A, Chiari L, D'Ascanio I, Eskofier B, Fernstad S, Froehlich M, Garcia-Aymerich J, Hansen C, Hausdorff JM, Hiden H, Hume E, Keogh A, Kluge F, Koch S, Maetzler W, Megaritis D, Mueller A, Niessen M, Palmerini L, Schwickert L, Scott K, Sharrack B, Sillén H, Singleton D, Vereijken B, Vogiatzis I, Yarnall AJ, Rochester L, Mazzà C, Del Din S, Mobilise-D consortium:(2023)Assessing real-world gait with digital technology? Validation, insights and recommendations from the Mobilise-D consortium.J Neuroeng Rehabil. 2023;20(1):
Prigent G, Aminian K, Cereatti A, Salis F, Bonci T, Scott K, Mazzà C, Alcock L, Del Din S, Gazit E, Hansen C, Paraschiv-Ionescu A, Mobilise-D consortium:(2023)A robust walking detection algorithm using a single foot-worn inertial sensor: validation in real-life settings.Med Biol Eng Comput. 2023;61(9): 2341-2352
Bruckner S, Kolpak J, Michler F, Shanin N, Schober R, Hagelauer A, Weigel R, Gasner H, Winkler J, Eskofier BM, Vossiek M:(2023)A Wireless Joint Communication and Localization EMG-Sensing Concept for Movement Disorder AssessmentIEEE J. Electromagn. RF Microw. Med. Biol.. 2023;7(4): 440-449
Brittain G, Buckley E, Costa GD, Martinis M, Chakraborty S, Stuerner KH, Rothhammer V, Gassner H, Leocani L, Comi G, Becker C, Rochester L, Sharrack B:(2023)Mobilise-D: The largest observational trial of digital mobility outcome measures in multiple sclerosisJ Neurol Sci. 2023;455 Suppl S():
Sidoroff V, Bachmann P, Seppi K, Krismer F, Gassner H, Winkler J, Hergenroeder-Lenzner N, Teckenburg I, Ibrahim A, Eskofier B, Roth N, Klucken J, Buechner S, Benninger D, Aminian K, Wenning G, Raccagni C:(2023)Characterization of gait profiles in patients with atypical parkinsonian syndromesEur J Neurol. 2023;30 Suppl 1(): 714-715
González-Alvarado MN, Aprato J, Baumeister M, Lippert M, Ekici AB, Kirchner P, Welz T, Hoffmann A, Winkler J, Wegner M, Haase S, Linker RA:(2022)Oligodendrocytes regulate the adhesion molecule ICAM-1 in neuroinflammation.Glia. 2022;70(3): 522-535
Balta D, Zunke F:(2022)The role of lysosomes in alpha-synucleinopathies: a focus on glial cells.Neural Regen Res. 2022;17(7): 1486-1488
Stojkovska I, Wani WY, Zunke F, Belur NR, Pavlenko EA, Mwenda N, Sharma K, Francelle L, Mazzulli JR:(2022)Rescue of α-synuclein aggregation in Parkinson's patient neurons by synergistic enhancement of ER proteostasis and protein trafficking.Neuron. 2022;110(3): 436-451.e11
Masanetz RK, Winkler J, Winner B, Günther C, Süß P:(2022)The Gut-Immune-Brain Axis: An Important Route for Neuropsychiatric Morbidity in Inflammatory Bowel Disease.Int J Mol Sci. 2022;23(19):
Gaßner H, Friedrich J, Masuch A, Jukic J, Stallforth S, Regensburger M, Marxreiter F, Winkler J, Klucken J:(2022)The Effects of an Individualized Smartphone-Based Exercise Program on Self-defined Motor Tasks in Parkinson Disease: Pilot Interventional Study.JMIR Rehabil Assist Technol. 2022;9(4):
Seebauer L, Schneider Y, Drobny A, Plötz S, Koudelka T, Tholey A, Prots I, Winner B, Zunke F, Winkler J, Xiang W:(2022)Interaction of Alpha Synuclein and Microtubule Organization Is Linked to Impaired Neuritic Integrity in Parkinson's Patient-Derived Neuronal Cells.Int J Mol Sci. 2022;23(3):
Battis K, Florio JB, Mante M, Lana A, Naumann I, Gauer C, Lambrecht V, Müller SJ, Cobo I, Fixsen B, Kim HY, Masliah E, Glass CK, Schlachetzki JCM, Rissman RA, Winkler J, Hoffmann A:(2022)CSF1R-Mediated Myeloid Cell Depletion Prolongs Lifespan But Aggravates Distinct Motor Symptoms in a Model of Multiple System Atrophy.J Neurosci. 2022;42(40): 7673-7688
Prieto Huarcaya A, Drobny S, Marques ARA, Di Spiezio A, Dobert JP, Balta D, Werner C, Rizo T, Gallwitz L, Bub S, Stojkovska I, Belur NR, Fogh J, Mazzulli JR, Xiang W, Fulzele A, Dejung M, Sauer M, Winner B, Rose-John S, Arnold P, Saftig P, Zunke F:(2022)Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models.Autophagy. 2022;18(5): 1127-1151
Kluge A, Bunk J, Schaeffer E, Drobny A, Xiang W, Knacke H, Bub S, Lückstädt W, Arnold P, Lucius R, Berg D, Zunke F:(2022)Detection of neuron-derived pathological α-synuclein in blood.Brain. 2022;145(9): 3058-3071
Leupold L, Sigutova V, Gerasimova E, Regensburger M, Zundler S, Zunke F, Xiang W, Winner B, Prots I:(2022)The Quest for Anti-α-Synuclein Antibody Specificity-Lessons Learnt From Flow Cytometry Analysis.Front Neurol. 2022;13():
Ollenschläger M, Küderle A, Mehringer W, Seifer AK, Winkler J, Gaßner H, Kluge F, Eskofier BM:(2022)MaD GUI: An Open-Source Python Package for Annotation and Analysis of Time-Series Data.Sensors (Basel). 2022;22(15):
Rachinger N, Mittag N, Böhme-Schäfer I, Xiang W, Kuphal S, Bosserhoff AK:(2022)Alpha-Synuclein and Its Role in Melanocytes.Cells. 2022;11(13):
Schneider Y, Turan S, Koller A, Krumbiegel M, Farrell M, Plötz S, Winkler J, Xiang W:(2022)Generation of a homozygous and a heterozygous SNCA gene knockout human-induced pluripotent stem cell line by CRISPR/Cas9 mediated allele-specific tuning of SNCA expression.Stem Cell Res. 2022;65():
Pieger K, Schmitt V, Gauer C, Gießl N, Prots I, Winner B, Winkler J, Brandstätter JH, Xiang W:(2022)Translocation of Distinct Alpha Synuclein Species from the Nucleus to Neuronal Processes during Neuronal Differentiation.Biomolecules. 2022;12(8):
Regensburger M, Spatz IT, Ollenschläger M, Martindale CF, Lindeburg P, Kohl Z, Eskofier B, Klucken J, Schüle R, Klebe S, Winkler J, Gaßner H:(2022)Inertial Gait Sensors to Measure Mobility and Functioning in Hereditary Spastic Paraplegia: A Cross-Sectional Multicenter Clinical Study.Neurology. 2022;99(10): e1079-89
Ibrahim AA, Flachenecker F, Gaßner H, Rothhammer V, Klucken J, Eskofier BM, Kluge F:(2022)Short inertial sensor-based gait tests reflect perceived state fatigue in multiple sclerosis.Mult Scler Relat Disord. 2022;58():
Gaßner H, Trutt E, Seifferth S, Friedrich J, Zucker D, Salhani Z, Adler W, Winkler J, Jost WH:(2022)Treadmill training and physiotherapy similarly improve dual task gait performance: a randomized-controlled trial in Parkinson's disease.J Neural Transm. 2022;129(9): 1189-1200
Utz KS, Kohl Z, Marterstock DC, Doerfler A, Winkler J, Schmidt M, Regensburger M:(2022)Neuropsychology and MRI correlates of neurodegeneration in SPG11 hereditary spastic paraplegia.Orphanet J Rare Dis. 2022;17(1):
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Regensburger M, Krumm L, Schmidt MA, Schmid A, Spatz IT, Marterstock DC, Kopp C, Kohl Z, Doerfler A, Karrasch T, Winner B, Winkler J:(2022)Neurometabolic Dysfunction in SPG11 Hereditary Spastic Paraplegia.Nutrients. 2022;14(22):
Krach F, Stemick J, Boerstler T, Weiss A, Lingos I, Reischl S, Meixner H, Ploetz S, Farrell M, Hehr U, Kohl Z, Winner B, Winkler J:(2022)An alternative splicing modulator decreases mutant HTT and improves the molecular fingerprint in Huntington's disease patient neurons.Nat Commun. 2022;13(1):
Lanfer J, Kaindl J, Krumm L, Gonzalez Acera M, Neurath M, Regensburger M, Krach F, Winner B:(2022)Efficient and Easy Conversion of Human iPSCs into Functional Induced Microglia-like Cells.Int J Mol Sci. 2022;23(9):
Rizo T, Gebhardt L, Riedlberger J, Eberhardt E, Fester L, Alansary D, Winkler J, Turan S, Arnold P, Niemeyer BA, Fischer MJM, Winner B:(2022)Store-operated calcium entry is reduced in spastin-linked hereditary spastic paraplegia.Brain. 2022;145(9): 3131-3146
van den Hurk M, Lau S, Marchetto MC, Mertens J, Stern S, Corti O, Brice A, Winner B, Winkler J, Gage FH, Bardy C:(2022)Druggable transcriptomic pathways revealed in Parkinson's patient-derived midbrain neurons.NPJ Parkinsons Dis. 2022;8(1):
Krach F, Wheeler EC, Regensburger M, Boerstler T, Wend H, Vu AQ, Wang R, Reischl S, Boldt K, Batra R, Aigner S, Ravits J, Winkler J, Yeo GW, Winner B:(2022)Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis.Acta Neuropathol (Berl). 2022;144(3): 413-435
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Drobny A, Prieto Huarcaya S, Dobert J, Kluge A, Bunk J, Schlothauer T, Zunke F:(2022)The role of lysosomal cathepsins in neurodegeneration: Mechanistic insights, diagnostic potential and therapeutic approaches.BBA - MOL CELL RES. 2022;1869(7):
Socher E, Heger L, Paulsen F, Zunke F, Arnold P:(2022)Molecular dynamics simulations of the delta and omicron SARS-CoV-2 spike - ACE2 complexes reveal distinct changes between both variants.Comput Struct Biotechnol J. 2022;20(): 1168-1176
Stern S, Lau S, Manole A, Rosh I, Percia MM, Ben Ezer R, Shokhirev MN, Qiu F, Schafer S, Mansour AA, Mangan KP, Stern T, Ofer P, Stern Y, Diniz Mendes AP, Djamus J, Moore LR, Nayak R, Laufer SH, Aicher A, Rhee A, Wong TL, Nguyen T, Linker SB, Winner B, Freitas BC, Jones E, Sagi I, Bardy C, Brice A, Winkler J, Marchetto MC, Gage FH:(2022)Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson's disease patients.NPJ Parkinsons Dis. 2022;8(1):
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Schmidt S, Luecken MD, Trümbach D, Hembach S, Niedermeier KM, Wenck N, Pflügler K, Stautner C, Böttcher A, Lickert H, Ramirez-Suastegui C, Ahmad R, Ziller MJ, Fitzgerald JC, Ruf V, van de Berg WDJ, Jonker AJ, Gasser T, Winner B, Winkler J, Vogt Weisenhorn DM, Giesert F, Theis FJ, Wurst W:(2022)Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease.Nat Commun. 2022;13(1):
Haberkorn B, Oswald S, Kehl N, Gessner A, Taudte RV, Dobert JP, Zunke F, Fromm MF, König J:(2022)Cancer-type organic anion transporting polypeptide 1B3 (Ct-OATP1B3) is localized in lysosomes and mediates resistance against kinase inhibitors.Mol Pharmacol. 2022;102(6): 248-258
Fröhlich H, Bontridder N, Petrovska-Delacréta D, Glaab E, Kluge F, Yacoubi ME, Marín Valero M, Corvol JC, Eskofier B, Van Gyseghem JM, Lehericy S, Winkler J, Klucken J:(2022)Leveraging the Potential of Digital Technology for Better Individualized Treatment of Parkinson's Disease.Front Neurol. 2022;13():
Nüssel M, Zhao Y, Knorr C, Regensburger M, Stadlbauer A, Buchfelder M, Del Vecchio A, Kinfe T:(2022)Deep Brain Stimulation, Stereotactic Radiosurgery and High-Intensity Focused Ultrasound Targeting the Limbic Pain Matrix: A Comprehensive Review.Pain Ther. 2022;11(2): 459-476
Roth N, Ullrich M, Kuderle A, Gladow T, Marxreiter F, Gassner H, Kluge F, Klucken J, Eskofier BM:(2022)Real-World Stair Ambulation Characteristics Differ Between Prospective Fallers and Non-Fallers in Parkinson's Disease.IEEE J Biomed Health Inform. 2022;26(9): 4733-4742
Suess P, Masanetz R, Baum W, Schett G, Schlachetzki J, Winkler J:(2022)The transcriptional regulator DREAM modulates glial cell proliferation dependent on the regional inflammatory microenvironmentJ Neurochem. 2022;162 Suppl 1(): 143-143
Reichmann H, Csoti I, Koschel J, Lorenzl S, Schrader C, Winkler J, Wüllner U:(2022)Life style and Parkinson's disease.J Neural Transm. 2022;129(9): 1235-1245
Marxreiter F, Koch V, Regensburger M, Stallforth S, Jukic J, Klucken J, Winkler J, Gassner H:(2022)Monitoring disease course by sensor-based gait analysis: gait symmetry and motor impairment progression in Parkinson's diseaseMov Disord. 2022;37 Suppl 2(): S505-S505
Mikolaizak AS, Rochester L, Maetzler W, Sharrack B, Demeyer H, Mazzà C, Caulfield B, Garcia-Aymerich J, Vereijken B, Arnera V, Miller R, Piraino P, Ammour N, Gordon MF, Troosters T, Yarnall AJ, Alcock L, Gaßner H, Winkler J, Klucken J, Schlenstedt C, Watz H, Kirsten AM, Vogiatzis I, Chynkiamis N, Hume E, Megaritis D, Nieuwboer A, Ginis P, Buckley E, Brittain G, Comi G, Leocani L, Helbostad JL, Johnsen LG, Taraldsen K, Blain H, Driss V, Frei A, Puhan MA, Polhemus A, Bosch de Basea M, Gimeno E, Hopkinson NS, Buttery SC, Hausdorff JM, Mirelman A, Evers J, Neatrour I, Singleton D, Schwickert L, Becker C, Jansen CP, clinical validation study (WP4) on behalf of Mobilise-D consortium:(2022)Connecting real-world digital mobility assessment to clinical outcomes for regulatory and clinical endorsement-the Mobilise-D study protocol.PLoS ONE. 2022;17(10):
Sidoroff V, Raccagni C, Kaindlstorfer C, Eschlboeck S, Fanciulli A, Granata R, Eskofier B, Seppi K, Poewe W, Willeit J, Kiechl S, Mahlknecht P, Stockner H, Marini K, Schorr O, Rungger G, Klucken J, Wenning G, Gaßner H:(2021)Characterization of gait variability in multiple system atrophy and Parkinson's disease.J Neurol. 2021;268(5): 1770-1779
Eggers C, Wellach I, Groppa S, Strothjohann M, Klucken J:(2021)[Care of patients with Parkinson's disease in Germany: status quo and perspectives as reflected in the digital transition].Nervenarzt. 2021;92(6): 602-610
Nuber S, Nam AY, Rajsombath MM, Cirka H, Hronowski X, Wang J, Hodgetts K, Kalinichenko LS, Müller CP, Lambrecht V, Winkler J, Weihofen A, Imberdis T, Dettmer U, Fanning S, Selkoe DJ:(2021)A Stearoyl-Coenzyme A Desaturase Inhibitor Prevents Multiple Parkinson Disease Phenotypes in α-Synuclein Mice.Ann Neurol. 2021;89(1): 74-90
Lückstädt W, Bub S, Koudelka T, Pavlenko E, Peters F, Somasundaram P, Becker-Pauly C, Lucius R, Zunke F, Arnold P:(2021)Cell Surface Processing of CD109 by Meprin β Leads to the Release of Soluble Fragments and Reduced Expression on Extracellular Vesicles.Front Cell Dev Biol. 2021;9():
Kluge F, Del Din S, Cereatti A, Gaßner H, Hansen C, Helbostad JL, Klucken J, Küderle A, Müller A, Rochester L, Ullrich M, Eskofier BM, Mazzà C, Mobilise-D consortium:(2021)Consensus based framework for digital mobility monitoring.PLoS ONE. 2021;16(8):
Polhemus A, Ortiz LD, Brittain G, Chynkiamis N, Salis F, Gaßner H, Gross M, Kirk C, Rossanigo R, Taraldsen K, Balta D, Breuls S, Buttery S, Cardenas G, Endress C, Gugenhan J, Keogh A, Kluge F, Koch S, Micó-Amigo ME, Nerz C, Sieber C, Williams P, Bergquist R, Bosch de Basea M, Buckley E, Hansen C, Mikolaizak AS, Schwickert L, Scott K, Stallforth S, van Uem J, Vereijken B, Cereatti A, Demeyer H, Hopkinson N, Maetzler W, Troosters T, Vogiatzis I, Yarnall A, Becker C, Garcia-Aymerich J, Leocani L, Mazzà C, Rochester L, Sharrack B, Frei A, Puhan M, Mobilise-D:(2021)Walking on common ground: a cross-disciplinary scoping review on the clinical utility of digital mobility outcomes.NPJ Digit Med. 2021;4(1):
Timotius IK, Bieler L, Couillard-Despres S, Sandner B, Garcia-Ovejero D, Labombarda F, Estrada V, Müller HW, Winkler J, Klucken J, Eskofier B, Weidner N, Puttagunta R:(2021)Combination of Defined CatWalk Gait Parameters for Predictive Locomotion Recovery in Experimental Spinal Cord Injury Rat Models.eNeuro. 2021;8(2):
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Reyes JF, Ekmark-Léwen S, Perdiki M, Klingstedt T, Hoffmann A, Wiechec E, Nilsson P, Nilsson KPR, Alafuzoff I, Ingelsson M, Hallbeck M:(2021)Accumulation of alpha-synuclein within the liver, potential role in the clearance of brain pathology associated with Parkinson's disease.Acta Neuropathol Commun. 2021;9(1):
Bunk J, Prieto Huarcaya S, Drobny A, Dobert JP, Walther L, Rose-John S, Arnold P, Zunke F:(2021)Corrigendum: Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties.Front Cell Dev Biol. 2021;9():
Bunk J, Prieto Huarcaya S, Drobny A, Dobert JP, Walther L, Rose-John S, Arnold P, Zunke F:(2021)Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties.Front Cell Dev Biol. 2021;9():
Zunke F, Winner B, Richter F, Caraveo G:(2021)Editorial: Intracellular Mechanisms of α-Synuclein Processing.Front Cell Dev Biol. 2021;9():
Krumm L, Pozner T, Kaindl J, Regensburger M, Günther C, Turan S, Asadollahi R, Rauch A, Winner B:(2021)Generation and characterization of an endogenously tagged SPG11-human iPSC line by CRISPR/Cas9 mediated knock-in.Stem Cell Res. 2021;56():
Quick S, Heidrich FM, Winkler MV, Winkler AH, Ibrahim K, Linke A, Speiser U, Grabmaier U, Buhmann C, Marxreiter F, Saft C, Danek A, Hermann A, Peikert K:(2021)Cardiac manifestation is evident in chorea-acanthocytosis but different from McLeod syndrome.Parkinsonism Relat Disord. 2021;88(): 90-95
Alvarado MNG, Aprato J, Baumeister M, Ekici A, Kirchner P, Hoffmann A, Winkler J, Wegner M, Haase S, Linker R:(2021)Oligodendrocytes regulate the adhesion molecule ICAM-1 in neuroinflammationGlia. 2021;69 Suppl 1(): E445-E446
German A, Mennecke A, Martin J, Hanspach J, Liebert A, Herrler J, Kuder TA, Schmidt M, Nagel A, Uder M, Doerfler A, Winkler J, Zaiss M, Laun FB:(2021)Brain tissues have single-voxel signatures in multi-spectral MRI.Neuroimage. 2021;234():
Chanoumidou K, Hernández-Rodríguez B, Windener F, Thomas C, Stehling M, Mozafari S, Albrecht S, Ottoboni L, Antel J, Kim KP, Velychko S, Cui QL, Xu YKT, Martino G, Winkler J, Schöler HR, Baron-Van Evercooren A, Boespflug-Tanguy O, Vaquerizas JM, Ehrlich M, Kuhlmann T:(2021)One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2.Stem Cell Reports. 2021;16(4): 771-783
Roth N, Wieland GP, Kuderle A, Ullrich M, Gladow T, Marxreiter F, Klucken J, Eskofier BM, Kluge F:(2021)Do We Walk Differently at Home? A Context-Aware Gait Analysis System in Continuous Real-World Environments.Annu Int Conf IEEE Eng Med Biol Soc. 2021;2021(): 1932-1935
Wanner P, Winterholler M, Gaßner H, Winkler J, Klucken J, Pfeifer K, Steib S:(2021)Acute exercise following skill practice promotes motor memory consolidation in Parkinson's disease.Neurobiol Learn Mem. 2021;178():
Gaßner H, Jensen D, Marxreiter F, Kletsch A, Bohlen S, Schubert R, Muratori LM, Eskofier B, Klucken J, Winkler J, Reilmann R, Kohl Z:(2020)Gait variability as digital biomarker of disease severity in Huntington's disease.J Neurol. 2020;267(6): 1594-1601
Martindale C, Roth N, Gassner H, List J, Regensburger M, Eskofier BM, Kohl Z:(2020)Technical Validation of an Automated Mobile Gait Analysis System for Hereditary Spastic Paraplegia Patients.IEEE J Biomed Health Inform. 2020;24(5): 1490-1499
Schink K, Gaßner H, Reljic D, Herrmann HJ, Kemmler W, Schwappacher R, Meyer J, Eskofier BM, Winkler J, Neurath MF, Klucken J, Zopf Y:(2020)Assessment of gait parameters and physical function in patients with advanced cancer participating in a 12-week exercise and nutrition programme: A controlled clinical trial.Eur J Cancer Care (Engl). 2020;29(2):
Marxreiter F, Buttler U, Gassner H, Gandor F, Gladow T, Winkler J, Ebersbach G, Klucken J:(2020)The Use of Digital Technology and Media in German Parkinson's Disease Patients.J Parkinsons Dis. 2020;10(2): 717-727
Regensburger M:(2020)Which kinds of fasciculations are missed by ultrasonography in ALS?Clin Neurophysiol. 2020;131(1): 237-238
Flachenecker F, Gaßner H, Hannik J, Lee DH, Flachenecker P, Winkler J, Eskofier B, Linker RA, Klucken J:(2020)Objective sensor-based gait measures reflect motor impairment in multiple sclerosis patients: Reliability and clinical validation of a wearable sensor device.Mult Scler Relat Disord. 2020;39():
Regensburger M, Stemick J, Masliah E, Kohl Z, Winner B:(2020)Intracellular A53T Mutant α-Synuclein Impairs Adult Hippocampal Newborn Neuron Integration.Front Cell Dev Biol. 2020;8():
Marxreiter F, Stemick J, Kohl Z:(2020)Huntingtin Lowering Strategies.Int J Mol Sci. 2020;21(6):
Dobert JP, Cabron AS, Arnold P, Pavlenko E, Rose-John S, Zunke F:(2020)Functional Characterization of Colon-Cancer-Associated Variants in ADAM17 Affecting the Catalytic Domain.Biomedicines. 2020;8(11):
Simmnacher K, Krach F, Schneider Y, Alecu JE, Mautner L, Klein P, Roybon L, Prots I, Xiang W, Winner B:(2020)Unique signatures of stress-induced senescent human astrocytes.Exp Neurol. 2020;334():
Stemick J, Gauer C, Wihan J, Moceri S, Xiang W, von Hörsten S, Kohl Z, Winkler J:(2020)Compensatory neuritogenesis of serotonergic afferents within the striatum of a transgenic rat model of Parkinson's disease.Brain Res. 2020;1748():
Eymsh B, Drobny A, Heyn TR, Xiang W, Lucius R, Schwarz K, Keppler JK, Zunke F, Arnold P:(2020)Toxic Metamorphosis-How Changes from Lysosomal to Cytosolic pH Modify the Alpha-Synuclein Aggregation Pattern.Biomacromolecules. 2020;21(12): 4673-4684
Mészáros L, Hoffmann A, Wihan J, Winkler J:(2020)Current Symptomatic and Disease-Modifying Treatments in Multiple System Atrophy.Int J Mol Sci. 2020;21(8):
Brazdis RM, Alecu JE, Marsch D, Dahms A, Simmnacher K, Lörentz S, Brendler A, Schneider Y, Marxreiter F, Roybon L, Winner B, Xiang W, Prots I:(2020)Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson's disease.Hum Mol Genet. 2020;29(7): 1180-1191
Süß P, Hoffmann A, Rothe T, Ouyang Z, Baum W, Staszewski O, Schett G, Prinz M, Krönke G, Glass CK, Winkler J, Schlachetzki JCM:(2020)Chronic Peripheral Inflammation Causes a Region-Specific Myeloid Response in the Central Nervous System.Cell Rep. 2020;30(12): 4082-4095.e6
Süß P, Rothe T, Hoffmann A, Schlachetzki JCM, Winkler J:(2020)The Joint-Brain Axis: Insights From Rheumatoid Arthritis on the Crosstalk Between Chronic Peripheral Inflammation and the Brain.Front Immunol. 2020;11():
Endres D, Decher N, Röhr I, Vowinkel K, Domschke K, Komlosi K, Tzschach A, Gläser B, Schiele MA, Runge K, Süß P, Schuchardt F, Nickel K, Stallmeyer B, Rinné S, Schulze-Bahr E, Tebartz van Elst L:(2020)New Cav1.2 Channelopathy with High-Functioning Autism, Affective Disorder, Severe Dental Enamel Defects, a Short QT Interval, and a Novel CACNA1C Loss-Of-Function Mutation.Int J Mol Sci. 2020;21(22):
Endres D, Prüss H, Rauer S, Süß P, Venhoff N, Feige B, Schweizer T, Nickel K, Maier S, Egger K, Domschke K, Meyer PT, Tebartz van Elst L:(2020)Probable Autoimmune Catatonia With Antibodies Against Cilia on Hippocampal Granule Cells and Highly Suspicious Cerebral FDG-Positron Emission Tomography Findings.Biol Psychiatry. 2020;87(9): e29-e31
Endres D, Rauer S, Venhoff N, Süß P, Dersch R, Runge K, Fiebich BL, Nickel K, Matysik M, Maier S, Domschke K, Egger K, Prüss H, van Elst LT:(2020)Probable Autoimmune Depression in a Patient With Multiple Sclerosis and Antineuronal Antibodies.Front Psychiatry. 2020;11():
Kuzior H, Fiebich BL, Yousif NM, Saliba SW, Ziegler C, Nickel K, Maier SJ, Süß P, Runge K, Matysik M, Dersch R, Berger B, Robinson T, Venhoff N, Kessler F, Blank T, Domschke K, Tebartz van Elst L, Endres D:(2020)Increased IL-8 concentrations in the cerebrospinal fluid of patients with unipolar depression.Compr Psychiatry. 2020;102():
Endres D, Rauer S, Pschibul A, Süß P, Venhoff N, Runge K, Feige B, Denzel D, Nickel K, Schweizer T, Maier S, Egger K, Domschke K, Meyer PT, Prüss H, Tebartz van Elst L:(2020)Novel Antineuronal Autoantibodies With Somatodendritic Staining Pattern in a Patient With Autoimmune Psychosis.Front Psychiatry. 2020;11():
Süß P, Schlachetzki JCM:(2020)Microglia in Alzheimer's Disease.Curr Alzheimer Res. 2020;17(1): 29-43
Kuhbandner K, Hoffmann A, González Alvarado MN, Seyler L, Bäuerle T, Winkler J, Linker RA:(2020)alpha-Synuclein: a Modulator During Inflammatory CNS Demyelination.J Mol Neurosci. 2020;70(7): 1038-1049
Lambrecht V, Hanspach J, Hoffmann A, Seyler L, Mennecke A, Straub S, Marxreiter F, Bäuerle T, Laun FB, Winkler J:(2020)Quantitative susceptibility mapping depicts severe myelin deficit and iron deposition in a transgenic model of multiple system atrophy.Exp Neurol. 2020;329():
Gaßner H, Jensen D, Marxreiter F, Kletsch A, Bohlen S, Schubert R, Muratori LM, Eskofier B, Klucken J, Winkler J, Reilmann R, Kohl Z:(2020)Correction to: Gait variability as digital biomarker of disease severity in Huntington's disease.J Neurol. 2020;267(6): 1602-1602
Cosma-Grigorov A, Meixner H, Mrochen A, Wirtz S, Winkler J, Marxreiter F:(2020)Changes in Gastrointestinal Microbiome Composition in PD: A Pivotal Role of Covariates.Front Neurol. 2020;11():
Gaßner H, Sanders P, Dietrich A, Marxreiter F, Eskofier BM, Winkler J, Klucken J:(2020)Clinical Relevance of Standardized Mobile Gait Tests. Reliability Analysis Between Gait Recordings at Hospital and Home in Parkinson's Disease: A Pilot Study.J Parkinsons Dis. 2020;10(4): 1763-1773
Ullrich M, Kuderle A, Hannink J, Din SD, Gasner H, Marxreiter F, Klucken J, Eskofier BM, Kluge F:(2020)Detection of Gait From Continuous Inertial Sensor Data Using Harmonic Frequencies.IEEE J Biomed Health Inform. 2020;24(7): 1869-1878
Piot I, Schweyer K, Respondek G, Stamelou M, DescribePSP study group , ProPSP study group , MDS-endorsed PSP study group , Sckopke P, Schenk T, Goetz CG, Stebbins GT, Höglinger GU, Gasser T, Hermann A, Höglinger G, Höllerhage M, Kimmich O, Klockgether T, Levin J, Machetanz G, Osterrath A, Palleis C, Prudlo J, Spottke A, Berg D, Bürk K, Claßen J, Eggers C, Greuel A, Grimm MJ, Hermann L, Iankova V, Jahn K, Jost W, Klietz M, Kühn A, Marxreiter F, Paschen S, Poetter-Nerger M, Preisl MT, Prilop L, Tönges L, Trenkwalder C, Warnecke T, Wegner F, Winkler J, Antonini A, P KP, L AL, Colosimo C, Compta Y, Corvol JC, I LI, Höglinger GU, E AE, Litvan I, R HR, Nilsson C, Pantelyat A, Respondek G, Stamelou M:(2020)The Progressive Supranuclear Palsy Clinical Deficits Scale.Mov Disord. 2020;35(4): 650-661
Regensburger M, Schlachetzki JCM, Klekamp J, Doerfler A, Winkler J:(2020)Long-term course of anterior spinal cord herniation presenting with an upper motor neuron syndrome: case report illustrating diagnostic and therapeutic implications.BMC Neurol. 2020;20(1):
Pozner T, Regensburger M, Engelhorn T, Winkler J, Winner B:(2020)Janus-faced spatacsin (SPG11): involvement in neurodevelopment and multisystem neurodegeneration.Brain. 2020;143(8): 2369-2379
Regensburger M, Minakaki G, Kettwig M, Huchzermeyer C, Eisenhut F, Haack TB, Kohl Z, Winkler J:(2020)Novel Biallelic CTSD Gene Variants Cause Late-Onset Ataxia and Retinitis Pigmentosa.Mov Disord. 2020;35(7): 1280-1282
Polhemus AM, Bergquist R, Bosch de Basea M, Brittain G, Buttery SC, Chynkiamis N, Dalla Costa G, Delgado Ortiz L, Demeyer H, Emmert K, Garcia Aymerich J, Gassner H, Hansen C, Hopkinson N, Klucken J, Kluge F, Koch S, Leocani L, Maetzler W, Micó-Amigo ME, Mikolaizak AS, Piraino P, Salis F, Schlenstedt C, Schwickert L, Scott K, Sharrack B, Taraldsen K, Troosters T, Vereijken B, Vogiatzis I, Yarnall A, Mazza C, Becker C, Rochester L, Puhan MA, Frei A:(2020)Walking-related digital mobility outcomes as clinical trial endpoint measures: protocol for a scoping review.BMJ Open. 2020;10(7):
Ibrahim AA, Küderle A, Gaßner H, Klucken J, Eskofier BM, Kluge F:(2020)Inertial sensor-based gait parameters reflect patient-reported fatigue in multiple sclerosis.J Neuroeng Rehabil. 2020;17(1):
Prell T, Siebecker F, Lorrain M, Tönges L, Warnecke T, Klucken J, Wellach I, Buhmann C, Wolz M, Lorenzl S, Herbst H, Eggers C, Mai T:(2020)Specialized Staff for the Care of People with Parkinson's Disease in Germany: An Overview.J Clin Med. 2020;9(8):
Radder DLM, Nonnekes J, van Nimwegen M, Eggers C, Abbruzzese G, Alves G, Browner N, Chaudhuri KR, Ebersbach G, Ferreira JJ, Fleisher JE, Fletcher P, Frazzitta G, Giladi N, Guttman M, Iansek R, Khandhar S, Klucken J, Lafontaine AL, Marras C, Nutt J, Okun MS, Parashos SA, Munneke M, Bloem BR:(2020)Recommendations for the Organization of Multidisciplinary Clinical Care Teams in Parkinson's Disease.J Parkinsons Dis. 2020;10(3): 1087-1098
Jacobs AH, Emmert K, Baron R, Bartsch T, Bauer J, Becker C, Berg D, Bergmann P, Boetzel K, Bollheimer C, Deuschl G, Djukic M, Drey M, Durwen H, Ebersbach G, Elshehabi M, Geritz J, Gisinger C, Guennewig T, Hauptmann B, Heppner HJ, Hobert MA, Hofmann W, Huellemann P, Jahn K, Klucken J, Kurth R, Lindner R, Lingor P, Lukas A, Maetzold S, Mokrusch T, Mollenhauer B, Nau R, Plate A, Polidori MC, Prell T, Schellinger P, Spira D, Stephani U, Studt S, Trenkwalder C, Unger HL, Urban P, von Arnim CAF, Warnecke T, Weiss M, Wiedemann A, Wirth R, Witt K, Dodel R, Maetzler W:(2020)Neurogeriatrics-a vision for improved care and research for geriatric patients with predominating neurological disabilities.Z Gerontol Geriatr. 2020;53(4): 340-346
Prell T, Siebecker F, Lorrain M, Eggers C, Lorenzl S, Klucken J, Warnecke T, Buhmann C, Tönges L, Ehret R, Wellach I, Wolz M:(2020)Recommendations for Standards of Network Care for Patients with Parkinson's Disease in Germany.J Clin Med. 2020;9(5):
Raccagni C, Sidoroff V, Goebel G, Granata R, Leys F, Klucken J, Eskofier B, Richer R, Seppi K, Wenning GK, Fanciulli A:(2020)The footprint of orthostatic hypotension in parkinsonian syndromes.Parkinsonism Relat Disord. 2020;77(): 107-109
Klucken J, Winkler J, Krüger R, Jost W:(2020)[The history of Freezing-of-gait in Parkinson's disease - from phenomena to symptom].Fortschr Neurol Psychiatr. 2020;88(9): 573-581
van Eimeren T, Claßen J, Drzezga A, Eggers C, Hilker-Roggendorf R, Klucken J, Koschel J, Meyer PT, Redecker C, Theis H, Buhmann C:(2020)[Recommendation for the differentiated use of nuclear medical diagnostic for parkinsonian syndromes].Fortschr Neurol Psychiatr. 2020;88(9): 609-619
Fischer S, Ullrich M, Kuderle A, Gasner H, Klucken J, Eskofier BM, Kluge F:(2020)Automatic clinical gait test detection from inertial sensor data.Annu Int Conf IEEE Eng Med Biol Soc. 2020;2020(): 789-792
Cerrone F, Pozner T, Siddiqui A, Ceppi P, Winner B, Rajendiran M, Babu R, Ibrahim HS, Rodriguez BJ, Winkler J, Murphy KJ, O'Connor KE:(2020)Polyhydroxyphenylvalerate/polycaprolactone nanofibers improve the life-span and mechanoresponse of human IPSC-derived cortical neuronal cells.Mater Sci Eng C Mater Biol Appl. 2020;111():
Starost L, Lindner M, Herold M, Xu YKT, Drexler HCA, Heß K, Ehrlich M, Ottoboni L, Ruffini F, Stehling M, Röpke A, Thomas C, Schöler HR, Antel J, Winkler J, Martino G, Klotz L, Kuhlmann T:(2020)Extrinsic immune cell-derived, but not intrinsic oligodendroglial factors contribute to oligodendroglial differentiation block in multiple sclerosis.Acta Neuropathol (Berl). 2020;140(5): 715-736
Aholt K, Eskofier BM, Martindale CF, Kuderle A, Gassner H, Gladow T, Rojo J, Villanueva-Mascato S, Klucken J, Arredondo Waldmeyer MT:(2019)A Mobile Solution for Rhythmic Auditory Stimulation Gait Training.Annu Int Conf IEEE Eng Med Biol Soc. 2019;2019(): 309-312
Perez-Branguli F, Buchsbaum IY, Pozner T, Regensburger M, Fan W, Schray A, Börstler T, Mishra H, Gräf D, Kohl Z, Winkler J, Berninger B, Cappello S, Winner B:(2019)Human SPG11 cerebral organoids reveal cortical neurogenesis impairment.Hum Mol Genet. 2019;28(6): 961-971
Kaindl J, Meiser I, Majer J, Sommer A, Krach F, Katsen-Globa A, Winkler J, Zimmermann H, Neubauer JC, Winner B:(2019)Zooming in on Cryopreservation of hiPSCs and Neural Derivatives: A Dual-Center Study Using Adherent Vitrification.Stem Cells Transl Med. 2019;8(3): 247-259
Minakaki G, Canneva F, Chevessier F, Bode F, Menges S, Timotius IK, Kalinichenko LS, Meixner H, Müller CP, Eskofier BM, Casadei N, Riess O, Schröder R, Winkler J, Xiang W, von Hörsten S, Klucken J:(2019)Treadmill exercise intervention improves gait and postural control in alpha-synuclein mouse models without inducing cerebral autophagy.Behav Brain Res. 2019;363(): 199-215
Gaßner H, Raccagni C, Eskofier BM, Klucken J, Wenning GK:(2019)The Diagnostic Scope of Sensor-Based Gait Analysis in Atypical Parkinsonism: Further Observations.Front Neurol. 2019;10():
Hoffmann AC, Minakaki G, Menges S, Salvi R, Savitskiy S, Kazman A, Vicente Miranda H, Mielenz D, Klucken J, Winkler J, Xiang W:(2019)Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose.Sci Rep. 2019;9(1):
Steib S, Klamroth S, Gaßner H, Pasluosta C, Eskofier B, Winkler J, Klucken J, Pfeifer K:(2019)Exploring gait adaptations to perturbed and conventional treadmill training in Parkinson's disease: Time-course, sustainability, and transfer.Hum Mov Sci. 2019;64(): 123-132
Strotzer QD, Anthofer JM, Faltermeier R, Brawanski AT, Torka E, Waldthaler JA, Kohl Z, Fellner C, Beer AL, Schlaier JR:(2019)Deep brain stimulation: Connectivity profile for bradykinesia alleviation.Ann Neurol. 2019;85(6): 852-864
Wihan J, Grosch J, Kalinichenko LS, Müller CP, Winkler J, Kohl Z:(2019)Layer-specific axonal degeneration of serotonergic fibers in the prefrontal cortex of aged A53T α-synuclein-expressing mice.Neurobiol Aging. 2019;80(): 29-37
Meents JE, Bressan E, Sontag S, Foerster A, Hautvast P, Rösseler C, Hampl M, Schüler H, Goetzke R, Le TKC, Kleggetveit IP, Le Cann K, Kerth C, Rush AM, Rogers M, Kohl Z, Schmelz M, Wagner W, Jørum E, Namer B, Winner B, Zenke M, Lampert A:(2019)The role of Nav1.7 in human nociceptors: insights from human induced pluripotent stem cell-derived sensory neurons of erythromelalgia patients.Pain. 2019;160(6): 1327-1341
Namer B, Schmidt D, Eberhardt E, Maroni M, Dorfmeister E, Kleggetveit IP, Kaluza L, Meents J, Gerlach A, Lin Z, Winterpacht A, Dragicevic E, Kohl Z, Schüttler J, Kurth I, Warncke T, Jorum E, Winner B, Lampert A:(2019)Pain relief in a neuropathy patient by lacosamide: Proof of principle of clinical translation from patient-specific iPS cell-derived nociceptors.EBioMedicine. 2019;39(): 401-408
Kalinichenko LS, Hammad L, Reichel M, Kohl Z, Gulbins E, Kornhuber J, Müller CP:(2019)Acid sphingomyelinase controls dopamine activity and responses to appetitive stimuli in mice.Brain Res Bull. 2019;146(): 310-319
Endres D, Rauer S, Kern W, Venhoff N, Maier SJ, Runge K, Süß P, Feige B, Nickel K, Heidt T, Domschke K, Egger K, Prüss H, Meyer PT, Tebartz van Elst L:(2019)Psychiatric Presentation of Anti-NMDA Receptor Encephalitis.Front Neurol. 2019;10():
List J, Kohl Z, Winkler J, Marxreiter F, Doerfler A, Schmidt MA:(2019)Ascending Axonal Degeneration of the Corticospinal Tract in Pure Hereditary Spastic Paraplegia: A Cross-Sectional DTI Study.Brain Sci. 2019;9(10):
Sommer A, Marxreiter F, Krach F, Fadler T, Grosch J, Maroni M, Graef D, Eberhardt E, Riemenschneider MJ, Yeo GW, Kohl Z, Xiang W, Gage FH, Winkler J, Prots I, Winner B:(2019)Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease.Cell Stem Cell. 2019;24(6):
Marxreiter F, Gassner H, Borozdina O, Barth J, Kohl Z, Schlachetzki J, Thun-Hohenstein C, Volc D, Eskofier B, Winkler J, Klucken J:(2019)Sensor-based gait analysis of individualized improvement during apomorphine titration in Parkinson's diseaseJ Neural Transm. 2019;126(5): 652-652
Gladow T, Gassner H, Ullrich M, Hannink J, Roth N, Marxreiter F, Kuederle A, Kohl Z, Winkler J, Eskofier B, Klucken J:(2019)Sensor-based gait analysis distinguishes fallers from non-fallers in Parkinson's disease under clinical and real-life conditionsJ Neural Transm. 2019;126(5): 657-657
Wihan J, Grosch J, Kalinichenko LS, Mueller C, Winkler J, Kohl Z:(2019)Layer-specific axonal degeneration of serotonergic fibers in the prefrontal cortex of transgenic A53T alpha-synuclein miceJ Neural Transm. 2019;126(5): 667-667
Marxreiter F, Utz K, Schlachetzki JCM, Seifert F, Schmidt M, Doerfler A, Schwab S, Schenk T:(2019)Transient naming deficits associated with insular lesions in a patient with encephalitis.Neurocase. 2019;25(6): 243-250
Reyes JF, Sackmann C, Hoffmann A, Svenningsson P, Winkler J, Ingelsson M, Hallbeck M:(2019)Binding of α-synuclein oligomers to Cx32 facilitates protein uptake and transfer in neurons and oligodendrocytes.Acta Neuropathol (Berl). 2019;138(1): 23-47
Gaßner H, Steib S, Klamroth S, Pasluosta CF, Adler W, Eskofier BM, Pfeifer K, Winkler J, Klucken J:(2019)Perturbation Treadmill Training Improves Clinical Characteristics of Gait and Balance in Parkinson's Disease.J Parkinsons Dis. 2019;9(2): 413-426
Nguyen A, Roth N, Ghassemi NH, Hannink J, Seel T, Klucken J, Gassner H, Eskofier BM:(2019)Development and clinical validation of inertial sensor-based gait-clustering methods in Parkinson's disease.J Neuroeng Rehabil. 2019;16(1):
Raccagni C, Goebel G, Gaßner H, Granata R, Ndayisaba JP, Seebacher B, Schoenherr G, Mitterhuber J, Hendriks P, Kaindlstorfer C, Eschlboeck S, Fanciulli A, Krismer F, Seppi K, Poewe W, Bloem BR, Klucken J, Wenning GK:(2019)Physiotherapy improves motor function in patients with the Parkinson variant of multiple system atrophy: A prospective trial.Parkinsonism Relat Disord. 2019;67(): 60-65
Kuhbandner K, Hammer A, Haase S, Terbrack E, Hoffmann A, Schippers A, Wagner N, Hussain RZ, Miller-Little WA, Koh AY, Stoolman JS, Segal BM, Linker RA, Stüve O:(2019)MAdCAM-1-Mediated Intestinal Lymphocyte Homing Is Critical for the Development of Active Experimental Autoimmune Encephalomyelitis.Front Immunol. 2019;10():
Hoffmann A, Ettle B, Battis K, Reiprich S, Schlachetzki JCM, Masliah E, Wegner M, Kuhlmann T, Riemenschneider MJ, Winkler J:(2019)Oligodendroglial α-synucleinopathy-driven neuroinflammation in multiple system atrophy.Brain Pathol. 2019;29(3): 380-396
Haji Ghassemi N, Hannink J, Roth N, Gaßner H, Marxreiter F, Klucken J, Eskofier BM:(2019)Turning Analysis during Standardized Test Using On-Shoe Wearable Sensors in Parkinson's Disease.Sensors (Basel). 2019;19(14):
Nguyen A, Roth N, Ghassemi NH, Hannink J, Seel T, Klucken J, Gassner H, Eskofier BM:(2019)Correction to: Development and clinical validation of inertial sensor-based gait-clustering methods in Parkinson's disease.J Neuroeng Rehabil. 2019;16(1):
Klamroth S, Gaßner H, Winkler J, Eskofier B, Klucken J, Pfeifer K, Steib S:(2019)Interindividual Balance Adaptations in Response to Perturbation Treadmill Training in Persons With Parkinson Disease.J Neurol Phys Ther. 2019;43(4): 224-232
Marxreiter F, Cosma-Grigorov A, Gassner H, Meixner H, Kohl Z, Neurath M, Wirtz S, Winkler J:(2019)Gastrointestinal microbiome in Parkinson's disease in a Bavarian cohortMov Disord. 2019;34(): S651-S651
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Minakaki G, Menges S, Kittel A, Emmanouilidou E, Schaeffner I, Barkovits K, Bergmann A, Rockenstein E, Adame A, Marxreiter F, Mollenhauer B, Galasko D, Buzás EI, Schlötzer-Schrehardt U, Marcus K, Xiang W, Lie DC, Vekrellis K, Masliah E, Winkler J, Klucken J:(2018)Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype.Autophagy. 2018;14(1): 98-119
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Krach F, Batra R, Wheeler EC, Vu AQ, Wang R, Hutt K, Rabin SJ, Baughn MW, Libby RT, Diaz-Garcia S, Stauffer J, Pirie E, Saberi S, Rodriguez M, Madrigal AA, Kohl Z, Winner B, Yeo GW, Ravits J:(2018)Transcriptome-pathology correlation identifies interplay between TDP-43 and the expression of its kinase CK1E in sporadic ALSActa Neuropathol (Berl). 2018;136(3): 405-423
Martindale CF, Roth N, Gasner H, Jensen D, Kohl Z, Eskofier BM:(2018)Mobile Gait Analysis using Personalised Hidden Markov Models for Hereditary Spastic Paraplegia Patients.Conf Proc IEEE Eng Med Biol Soc. 2018;2018(): 5430-5433
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Kluge F, Hannink J, Pasluosta C, Klucken J, Gaßner H, Gelse K, Eskofier BM, Krinner S:(2018)Pre-operative sensor-based gait parameters predict functional outcome after total knee arthroplasty.Gait Posture. 2018;66(): 194-200
Klucken J, Krüger R, Schmidt P, Bloem BR:(2018)Management of Parkinson's Disease 20 Years from Now: Towards Digital Health Pathways.J Parkinsons Dis. 2018;8(s1): S85-S94
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Witchel HJ, Oberndorfer C, Needham R, Healy A, Westling CEI, Guppy JH, Bush J, Barth J, Herberz C, Roggen D, Eskofier BM, Rashid W, Chockalingam N, Klucken J:(2018)Thigh-Derived Inertial Sensor Metrics to Assess the Sit-to-Stand and Stand-to-Sit Transitions in the Timed Up and Go (TUG) Task for Quantifying Mobility Impairment in Multiple Sclerosis.Front Neurol. 2018;9():
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Weider M, Starost LJ, Groll K, Küspert M, Sock E, Wedel M, Fröb F, Schmitt C, Baroti T, Hartwig AC, Hillgärtner S, Piefke S, Fadler T, Ehrlich M, Ehlert C, Stehling M, Albrecht S, Jabali A, Schöler HR, Winkler J, Kuhlmann T, Wegner M:(2018)Publisher Correction: Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning.Nat Commun. 2018;9(1):
Gaßner H, Marxreiter F, Steib S, Kohl Z, Schlachetzki JCM, Adler W, Eskofier BM, Pfeifer K, Winkler J, Klucken J:(2017)Gait and Cognition in Parkinson's Disease: Cognitive Impairment Is Inadequately Reflected by Gait Performance during Dual Task.Front Neurol. 2017;8():
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Schmidt MA, Engelhorn T, Marxreiter F, Winkler J, Lang S, Kloska S, Goelitz P, Doerfler A:(2017)Ultra high-field SWI of the substantia nigra at 7T: reliability and consistency of the swallow-tail sign.BMC Neurol. 2017;17(1):
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Allison R, Edgar JR, Pearson G, Rizo T, Newton T, Günther S, Berner F, Hague J, Connell JW, Winkler J, Lippincott-Schwartz J, Beetz C, Winner B, Reid E:(2017)Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia.J Cell Biol. 2017;216(5): 1337-1355
Steib S, Klamroth S, Gaßner H, Pasluosta C, Eskofier B, Winkler J, Klucken J, Pfeifer K:(2017)Perturbation During Treadmill Training Improves Dynamic Balance and Gait in Parkinson's Disease: A Single-Blind Randomized Controlled Pilot Trial.Neurorehabil Neural Repair. 2017;31(8): 758-768
Hannink J, Ollenschläger M, Kluge F, Roth N, Klucken J, Eskofier BM:(2017)Benchmarking Foot Trajectory Estimation Methods for Mobile Gait Analysis.Sensors (Basel). 2017;17(9):
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Frentzel D, Judanin G, Borozdina O, Klucken J, Winkler J, Schlachetzki JCM:(2017)Increase of Reproductive Life Span Delays Age of Onset of Parkinson's Disease.Front Neurol. 2017;8():
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Regensburger M, Türk M, Pagenstecher A, Schröder R, Winkler J:(2017)VCP-related multisystem proteinopathy presenting as early-onset Parkinson disease.Neurology. 2017;89(7): 746-748
Schneider-Gold C, Dekomien G, Regensburger M, Schneider R, Trampe N, Krogias C, Lukas C, Bellenberg B:(2017)Monozygotic twins with a new compound heterozygous SPG11 mutation and different disease expression.J Neurol Sci. 2017;381(): 265-268
Marxreiter F, Winkler J, Uhl M, Madzar D:(2017)A Case Report of Severe Delirium after Amantadine Withdrawal.Case Rep Neurol. 2017;9(1): 44-48
Kohl Z, Schlachetzki JC, Feldewerth J, Hornauer P, Münch M, Adame A, Riemenschneider MJ, Winkler J, Masliah E:(2017)Distinct Pattern of Microgliosis in the Olfactory Bulb of Neurodegenerative Proteinopathies.Neural Plast. 2017;2017():
Lee DH, Seubert S, Huhn K, Brecht L, Rötger C, Waschbisch A, Schlachetzki J, Klausmeyer A, Melms A, Wiese S, Winkler J, Linker RA:(2017)Fingolimod effects in neuroinflammation: Regulation of astroglial glutamate transporters?PLoS ONE. 2017;12(3): e0171552
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Schlachetzki JC, Grimm T, Schlachetzki Z, Ben Abdallah NM, Ettle B, Vöhringer P, Ferger B, Winner B, Nuber S, Winkler J:(2016)Dopaminergic lesioning impairs adult hippocampal neurogenesis by distinct modification of ?-synuclein.J Neurosci Res. 2016;94(1): 62-73
Kohl Z, Ben Abdallah N, Vogelgsang J, Tischer L, Deusser J, Amato D, Anderson S, Müller CP, Riess O, Masliah E, Nuber S, Winkler J:(2016)Severely impaired hippocampal neurogenesis associates with an early serotonergic deficit in a BAC ?-synuclein transgenic rat model of Parkinson's disease.Neurobiol Dis. 2016;85(): 206-17
Mrochen A, Marxreiter F, Kohl Z, Schlachetzki J, Renner B, Schenk T, Winkler J, Klucken J:(2016)From sweet to sweat: Hedonic olfactory range is impaired in Parkinson's disease.Parkinsonism Relat Disord. 2016;22(): 9-14
Salvi R, Steigleder T, Schlachetzki JC, Waldmann E, Schwab S, Winner B, Winkler J, Kohl Z:(2016)Distinct Effects of Chronic Dopaminergic Stimulation on Hippocampal Neurogenesis and Striatal Doublecortin Expression in Adult Mice.Front Neurosci. 2016;10(): 77
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Emmanouilidou E, Minakaki G, Keramioti MV, Xylaki M, Balafas E, Chrysanthou-Piterou M, Kloukina I, Vekrellis K:(2016)GABA transmission via ATP-dependent K+ channels regulates α-synuclein secretion in mouse striatum.Brain. 2016;139(Pt 3): 871-90
Schulze M, Hoja S, Winner B, Winkler J, Edenhofer F, Riemenschneider MJ:(2016)Model Testing of PluriTest with Next-Generation Sequencing Data.Stem Cells Dev. 2016;25(7): 569-71
Marxreiter F, Storch A, Winkler J:(2016)[Cellular replacement strategies and adult neurogenesis in idiopathic Parkinson's disease].Nervenarzt. 2016;87(8): 805-13
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Hammer A, Yang G, Friedrich J, Kovacs A, Lee DH, Grave K, Jörg S, Alenina N, Grosch J, Winkler J, Gold R, Bader M, Manzel A, Rump LC, Müller DN, Linker RA, Stegbauer J:(2016)Role of the receptor Mas in macrophage-mediated inflammation in vivo.Proc Natl Acad Sci U S A. 2016;113(49): 14109-14114
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Ettle B, Kerman BE, Valera E, Gillmann C, Schlachetzki JC, Reiprich S, Büttner C, Ekici AB, Reis A, Wegner M, Bäuerle T, Riemenschneider MJ, Masliah E, Gage FH, Winkler J:(2016)α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy.Acta Neuropathol (Berl). 2016;132(1): 59-75
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Bensimon G, Ludolph A, Agid Y, Vidailhet M, Payan C, Leigh PN, NNIPPS Study Group:(2009)Riluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: the NNIPPS study.Brain. 2009;132(Pt 1): 156-71
Marxreiter F, Nuber S, Kandasamy M, Klucken J, Aigner R, Burgmayer R, Couillard-Despres S, Riess O, Winkler J, Winner B:(2009)Changes in adult olfactory bulb neurogenesis in mice expressing the A30P mutant form of alpha-synuclein.Eur J Neurosci. 2009;29(5): 879-90
Torner L, Karg S, Blume A, Kandasamy M, Kuhn HG, Winkler J, Aigner L, Neumann ID:(2009)Prolactin prevents chronic stress-induced decrease of adult hippocampal neurogenesis and promotes neuronal fate.J Neurosci. 2009;29(6): 1826-33
Winkelheide U, Lasarzik I, Kaeppel B, Winkler J, Werner C, Kochs E, Engelhard K:(2009)Dose-dependent effect of S(+) ketamine on post-ischemic endogenous neurogenesis in rats.Acta Anaesthesiol Scand. 2009;53(4): 528-33
Bauer P, Winner B, Schüle R, Bauer C, Häfele V, Hehr U, Bonin M, Walter M, Karle K, Ringer TM, Ries O, Winkler J, Schols L:(2009)Identification of a heterozygous genomic deletion in the spatacsin gene in SPG11 patients using high-resolution comparative genomic hybridization.Neurogenetics. 2009;10(1): 43-48
Rudnik-Schöneborn S, Hehr U, von Kalle T, Bornemann A, Winkler J, Zerres K:(2009)Andermann syndrome can be a phenocopy of hereditary motor and sensory neuropathy--report of a discordant sibship with a compound heterozygous mutation of the KCC3 gene.Neuropediatrics. 2009;40(3): 129-33
Regensburger M, Kohl Z, Grundmann K, Winner B, Riess O, Winkler J:(2009)Adult neural precursor cells unaffected in animal models of DYT1 dystonia.Neuroreport. 2009;20(17): 1529-33
Winner B, Desplats P, Hagl C, Klucken J, Aigner R, Ploetz S, Laemke J, Karl A, Aigner L, Masliah E, Buerger E, Winkler J:(2009)Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model.Exp Neurol. 2009;219(2): 543-52
Schüle R, Schlipf N, Synofzik M, Klebe S, Klimpe S, Hehr U, Winner B, Lindig T, Dotzer A, Riess O, Winkler J, Schols L, Bauer P:(2009)Frequency and phenotype of SPG11 and SPG15 in complicated hereditary spastic paraplegia.J Neurol Neurosurg Psychiatry. 2009;80(12): 1402-4
Outeiro TF, Klucken J, Bercury K, Tetzlaff J, Putcha P, Oliveira LM, Quintas A, McLean PJ, Hyman BT:(2009)Dopamine-induced conformational changes in alpha-synuclein.PLoS ONE. 2009;4(9): e6906
Winner B, Vogt-Weisenhorn DM, Lie CD, Blümcke I, Winkler J:(2009)Cellular repair strategies in Parkinson's disease.Therap Adv Neurol Dis. 2009;2(1): 51-60
Nuber S, Petrasch-Parwez E, Winner B, Winkler J, von Hörsten S, Schmidt T, Boy J, Kuhn M, Nguyen HP, Teismann P, Schulz JB, Neumann M, Pichler BJ, Reischl G, Holzmann C, Schmitt I, Bornemann A, Kuhn W, Zimmermann F, Servadio A, Riess O:(2008)Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease.J Neurosci. 2008;28(10): 2471-84
Audebert HJ, Boy S, Jankovits R, Pilz P, Klucken J, Fehm NP, Schenkel J:(2008)Is mobile teleconsulting equivalent to hospital-based telestroke services?Stroke. 2008;39(12): 3427-30
Hennemann B, Ickenstein G, Sauerbruch S, Luecke K, Haas S, Horn M, Andreesen R, Bogdahn U, Winkler J:(2008)Mobilization of CD34+ hematopoietic cells, colony-forming cells and long-term culture-initiating cells into the peripheral blood of patients with an acute cerebral ischemic insult.Cytotherapy. 2008;10(3): 303-11
Couillard-Despres S, Finkl R, Winner B, Ploetz S, Wiedermann D, Aigner R, Bogdahn U, Winkler J, Hoehn M, Aigner L:(2008)In vivo optical imaging of neurogenesis: watching new neurons in the intact brain.Mol Imaging. 2008;7(1): 28-34
Couillard-Despres S, Quehl E, Altendorfer K, Karl C, Ploetz S, Bogdahn U, Winkler J, Aigner L:(2008)Human in vitro reporter model of neuronal development and early differentiation processes.BMC Neurosci. 2008;9(): 31
Winkelheide U, Engelhard K, Kaeppel B, Winkler J, Hutzler P, Werner C, Kochs E:(2008)Cerebral ischemia and neurogenesis: a two-time comparison.Neurocrit Care. 2008;9(3): 387-93
Winner B, Rockenstein E, Lie DC, Aigner R, Mante M, Bogdahn U, Couillard-Despres S, Masliah E, Winkler J:(2008)Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis.Neurobiol Aging. 2008;29(6): 913-25
Schroeder C, Walter M, Berg D, Leitner P, Bauer P, Kohl Z, Winkler J, Riess O, Bonin M:(2008)High-throughput homogeneous mass cleave assay technology for the diagnosis of autosomal recessive Parkinson's disease.J Mol Diagn. 2008;10(3): 217-24
Winner B, Couillard-Despres S, Geyer M, Aigner R, Bogdahn U, Aigner L, Kuhn HG, Winkler J:(2008)Dopaminergic lesion enhances growth factor-induced striatal neuroblast migration.J Neuropathol Exp Neurol. 2008;67(2): 105-16
Crews L, Mizuno H, Desplats P, Rockenstein E, Adame A, Patrick C, Winner B, Winkler J, Masliah E:(2008)Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice.J Neurosci. 2008;28(16): 4250-60
Kohl Z, Winkler J, Koch HJ:(2008)Seasonal pattern of births in patients with idiopathic Parkinson syndromeBiol Rhythm Res. 2008;39(1): 39-41
Schlachetzki JC, Langosch JM:(2008)Aripiprazole induced hypersexuality in a 24-year-old female patient with schizoaffective disorder?J Clin Psychopharmacol. 2008;28(5): 567-8

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